Association of Long-term Conditions With Survival Following Acute Myocardial Infarction in England and Wales
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 693,633
- 主要终点
- Number of patients who died from any cause by the end of the study censoring period
研究概览
简要总结
This study aims to determine the extent to which pre-existing long-term conditions are associated with survival following a heart attack (acute myocardial infarction) using observational data from the UK's national heart attack register.
详细描述
Using observational data from the Myocardial Ischaemia National Audit Project (MINAP) of all hospitalisations for acute myocardial infarction in all acute hospitals in England and Wales, this study aims to determine the extent to which pre-existing long-term conditions are associated with survival following acute myocardial infarction. The study will include an investigation of individual long term conditions for patients with acute myocardial infarction, including chronic heart failure, cerebrovascular disease, diabetes mellitus, chronic obstructive pulmonary disease, chronic renal failure or peripheral vascular disease as well as the combination of such conditions and their resulting impact on long term all-cause mortality (up to 8.4 years). In addition, an investigation of the association of receipt of guideline recommended care for acute myocardial infarction patients with pre-existing long term conditions will be made.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients must be 18 years or older
排除标准
- •Patients for which mortality data are missing
结局指标
主要结局
Number of patients who died from any cause by the end of the study censoring period
时间窗: 8.4 years
Death data was obtained from national death records from the Office for National Statistics
次要结局
- Number of patients who received guideline recommended therapy during the study period(Any guideline therapy administered during the patients hospital admission for acute myocardial infarction, an average of 4 days)
研究者
Marlous Hall
Co-Investigator
University of Leeds