Feasibility of Remote Early At-risk Diagnosis for Cerebral Palsy in High-risk Infant Follow-up Clinics in The Central Norway Regional Health Authority

St. Olavs Hospital3 sites in 1 country100 target enrollmentAugust 3, 2020

ConditionsCerebral Palsy

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Cerebral Palsy
Sponsor: St. Olavs Hospital
Enrollment: 100
Locations: 3
Primary Endpoint: Predictability of GMA and computer-based assessment for development of CP
Status: Active, not recruiting
Last Updated: 10 months ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Cerebral Palsy (CP) is the most common motor dysfunction in childhood. Traditionally, diagnosis is set between 12 and 24 months of age. This study will evaluate feasibility of a new screening procedure for early detection of CP in high-risk infants and investigate how such a procedure can be implemented in the Central Norwegian Regional Health Authority (CNRHA).

The most accurate method to detect and predict CP at an early age is the General Movement Assessment (GMA). GMA is based upon expert observations of infant spontaneous movements in a video. In Central-Norway such expertise is today only present at St. Olavs Hospital, Trondheim University Hospital. Video recordings by health personnel and parents will be used in follow-up programs within CNRHA for remote expert based GMA. In addition, machine learning models will be applied for automatic detection of CP.

Early identification of CP will lead to improved function and increased possibility to direct health care resources to the patients who need it most, independent of geographical and expert based constraints.

Registry

clinicaltrials.gov

Start Date

August 3, 2020

End Date

December 2025

Last Updated

10 months ago

Study Type

Observational

Sex

All

Investigators

Sponsor

St. Olavs Hospital

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•hospitalized at a Neonatal Intensive Care Unit (NICU) within the Central Norway Regional Health Authority that is referred to follow-up in the Specialist Health Services containing a team of minimum a pediatrician and a physiotherapist.
•at high-risk for adverse neurological outcomes as considered by the pediatrician on the basis of clinical judgement (example: serious asphyxia, prematurity, stroke, brain hemorrhage)