The Effects of Upper Airway Muscle Training on Obstructive Sleep Apnoea (OSA) Severity and Upper Airway Physiology

Not Applicable

Recruiting

• Conditions: obstructive sleep apnoea; Respiratory - Sleep apnoea; Physical Medicine / Rehabilitation - Speech therapy

• Registration Number: ACTRN12620000818932
• Lead Sponsor: Flinders University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-08-17
• Last Update Posted: 24 August 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

Male or female
Otherwise healthy with a confirmed diagnosis of OSA.
AHI greater than 5 events/h on pre-training PSG night.
Currently not on treatment, or have previously failed treatment for OSA

Exclusion Criteria

Clinically significant craniofacial malformation.
Clinically significant cardiac disease (e.g., rhythm disturbances, coronary artery disease or cardiac failure) or hypertension requiring more than 2 medications for control.
Clinically significant neurological disorder, including epilepsy/convulsions.
Clinically significant cognitive dysfunction
Participants who have had upper airway surgery < 1 year prior to participation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Apnoea-Hypopnea Index (AHI) - the severity of sleep apnea, i.e. the number of apnea and hypopnea events during sleep. <br><br>[Measured before (week 1) and after (week 12) muscle training. ]