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临床试验/NCT05748964
NCT05748964尚未招募不适用

Different Surgical Approaches for Treatment of UPJ Obstruction in Children: Prospective Randomized Clinical Trial

Assiut University0 个研究点目标入组 20 人开始时间: 2023年4月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
20
主要终点
Operative time

研究概览

简要总结

This study aimed to evaluate the clinical efficacy of laparoscopic pyeloplasty (LP) for ureteropelvic junction obstruction (UPJO) via retroperitoneal and transperitoneal approaches.

详细描述

Ureteropelvic junction obstruction (UPJO) is the most common congenital abnormality of the kidney and is responsible for flank pain, recurrent urinary infections, hydronephrosis and the loss of renal function. Until recently, open pyeloplasty (OP) was the standard surgical treatment modality for UPJO.However, with the development of laparoscopic devices and surgical technology, laparoscopic pyeloplasty (LP) has become a more beneficial choice for the patients with UPJO than open surgery because of the advantages of excellent visualization, minimal trauma, rapid postoperative recovery, good cosmetic result, and a nearly successful rate compared with open pyeloplasty. The first LP in children was performed in 1995. It has gained popularity for older children. LP can be performed though retroperitoneal and transperitoneal approaches. Which surgical method is better is still controversial.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
2 Years 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Age above two years.
  • Unilateral UPJO.

排除标准

  • Age below two years.
  • Bilateral UPJO.
  • Recurrent UPJO.
  • Malrotated kidneys and renal fusion anomalies.

结局指标

主要结局

Operative time

时间窗: From April 1, 2023 to April 1, 2024

Operative time

次要结局

  • Hospital stay(From April 1, 2023 to April 1, 2024)
  • Post operative complications(From April 1, 2023 to April 1, 2024)
  • Convergence rate(From April 1, 2023 to April 1, 2024)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ahmed Kamel Ali Mohamed

Mr.

Assiut University

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