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Pronation in COVID-19 Patients Undergoing Non Invasive Respiratory Support

Completed
Conditions
Covid19
Interventions
Behavioral: Prone position
Registration Number
NCT04649658
Lead Sponsor
University of Modena and Reggio Emilia
Brief Summary

Pronation seems feasible and effective in improving blood oxygenation in patients with COVID-19 pneumonia. Data are lacking on the effects of pronation on clinical outcome in this subset of patients.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
93
Inclusion Criteria

Inclusion Criteria

  • patients aged ≥18 and < 80 years old
  • acute respiratory failure
Exclusion Criteria
  • endotracheal intubation performed within the first 24 hours from admission,
  • ceiling of escalation of intensive care
  • do not intubate order as expressed by patient willing or upon clinical judgement
  • missing core data at medical record analysis (clinical features at baseline, pronation information, type and time of ventilatory support required, mortality, need for tracheostomy, length of respiratory intensive care unit and hospital stay).

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Prone positionProne positionSevere and critical COVID-19 patients undergoing non invasive respiratory support subjected to prone position
Primary Outcome Measures
NameTimeMethod
Endotracheal intubation28 days
Secondary Outcome Measures
NameTimeMethod
Mortality28 days
Length of Respiratory Intensive Care Unit stay60 days
Length of Hospital stay60 days
Tracheostomy28 days

Trial Locations

Locations (1)

Azienda Ospedaliero Universitaria Policlinico di Modena

🇮🇹

Modena, Italy

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