Chest hyperinflation and response to corticosteroids and inhaled adrenaline in children with bronchiolitis admitted to intensive care

Royal Children's Hospital0 个研究点目标入组 211 人开始时间: 2023年3月25日最近更新: 2023年4月3日

适应症

试验速览

暂无简介。

•Children who were recruited in the DAB study (ACTRN12613000316707) and received a chest x ray
•The inclusion criteria were
•a clinical diagnosis of bronchiolitis, defined as a first or second episode of wheezing or
•respiratory distress associated with a respiratory tract infection plus either radiological
•evidence of chest hyperinflation or clinical evidence of prolonged expiration
•less than 18 months of age
•no previous enrolment to this study
•admission to intensive care for respiratory distress (not apnoea alone)
•recruitment and initiation of the study therapy within 4 hours of admission to intensive care

•Patients with the following will be excluded
•Corrected gestational age of less than 37 weeks at time of admission to the intensive care.
•Clinical evidence of croup (laryngotracheobronchitis)
•Received immunosuppressive treatment, including any dose of corticosteroids, in the last 7days.
•On ECMO or HFOV at the time of enrolment
•Previously enrolled in the study

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