Evaluation of a universal adhesive containing quercetin in non-carious cervical lesion restorations: a clinical trial.

Not Applicable

• Conditions: Tooth Abrasion,Tooth Attrition,Tooth Erosion

• Registration Number: RBR-6t3w7pt
• Lead Sponsor: niversidade Estadual de Ponta Grossa

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-08-16
• Last Update Posted: 19 August 2024
• Study Completion: 2029-12-12

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Participants with good general health; participants aged over 18 years to 60 years (men and women); acceptable level of oral hygiene; participants must present at least 20 teeth in occlusion; 20 teeth in function; no active clasps from removable partial dentures on the included teeth; the teeth should not be abutments for prostheses; absence of periodontal disease; no active carious lesions; no parafunctional habits; participants should have at least two non-carious cervical lesions (NCCLs) to be restored in different teeth; the lesions should be non-retentive; lesions deeper than 1 mm; lesions that involve both enamel and dentin of vital teeth; and the cavosurface margin should not involve more than 50% of the enamel

Exclusion Criteria

Participants with extremely poor oral hygiene; participants using orthodontic devices; participants with severe or chronic periodontitis; participants with parafunctional habits; participants with known allergies to resin-based materials or any other materials used in this study; pregnant women; breastfeeding women; participants on chronic use of anti-inflammatories, analgesics, and psychotropics; participants who have difficulty attending follow-up appointments after the restoration will also be excluded

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To clinically evaluate the performance retention rate of a universal adhesive system containing nanoencapsulated quercetin in the self-etch mode, in composite resin restorations of non-carious cervical lesions after baseline, 6, 12, 24, 36, 48, and 60 months, when compared to a universal adhesive system (without nanoencapsulated quercetin). The evaluations will be conducted using the World Federation Criteria (FDI) and United States Public Health Service (USPHS) criteria.

Secondary Outcome Measures

Name	Time	Method
To clinically evaluate the performance marginal discoloration and marginal adaptation, postoperative sensitivity, and recurrence of caries of a universal adhesive system containing nanoencapsulated quercetin in the self-etch mode, in composite resin restorations of non-carious cervical lesions after baseline, 6, 12, 24, 36, 48, and 60 months, when compared to a universal adhesive system (without nanoencapsulated quercetin). The evaluations will be conducted using the World Federation Criteria (FDI) and United States Public Health Service (USPHS).