A split-face study comparing the incidence of postinflammatory hyperpigmentation following a 532-nm Picosecond laser: broad-spectrum vs. broad-spectrum with iron oxide sunscreens
- Conditions
- Solar lentiginesPIHVisible lightSunscreen
- Registration Number
- TCTR20230417004
- Lead Sponsor
- Skinova Co., Ltd.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- All
- Target Recruitment
- 30
1. Asian with Fitzpatrick Skin type III-V
2. Was diagnosed by a physician as Solar lentigines
3. There are solar lentigines lesions on both sides of the face. The lesion size is greater than 6 mm.
1. Pregnant women
2. Patients with dermatitis, wounds, or skin infections on the face
3. Patients with a history of allergy to anesthetics that cannot use cold air during treatment instead.
4. Patients with a history of allergy to sunscreen or iron oxide allergy
5. Patients with other diseases related to pigmentation abnormalities, such as melasma, hori nevus, nevus of ota, freckles, etc., in the same area as solar lentigines
6. Patients with a history of herpes on the face or suffering from herpes on the face
7. Patients with mental disorders whom a psychiatrist has diagnosed.
8. Patients considered by the researcher to be unsafe if participating in the program
9. Patients who are not allowed to take pictures for treatment evaluation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of PIH 2 weeks, 4 weeks, 8 weeks, 12 weeks after treatment Clinical evaluation
- Secondary Outcome Measures
Name Time Method Average melanin concentration Before treatment, 2 weeks, 4 weeks, 8 weeks, 12 weeks after treatment Antera 3D analysis,Melanin index Before treatment, 2 weeks, 4 weeks, 8 weeks, 12 weeks after treatment Mexameter MX 18