To compare the effect of lying in face down position along with oxygen therapy given through high flow nasal cannula device versus lying face down with oxygen given by non-rebreathing face mask in COVID-19 patients.
Not Applicable
Suspended
- Conditions
- Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
- Registration Number
- CTRI/2020/12/029587
- Lead Sponsor
- All India Institute Of Medical Sciences Patna
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Suspended
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Adult Confirmed COIVD19 positive patients admitted to ICU for acute hypoxemic respiratory failure.
2. Acute hypoxemic respiratory failure defined by respiratory rate >=25 breaths/min, and PaO2/FiO2 <=300 mm Hg while spontaneously breathing under standard oxygen therapy.
Exclusion Criteria
1. BMI more than 40
2. Immediate need of intubation
3. Sign of respiratory failure (RR > 40/min, PaCO2 > 50 mmHg/pH < 7.30, and obvious accessory respiratory muscle use)
4. Unstable hemodynamic status
5. Impending cardiopulmonary arrest,
6. Glasgow coma scale score lower than 8.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the rates of intubation between the two groupsTimepoint: 28 days
- Secondary Outcome Measures
Name Time Method 1.To compare the arterial oxygen partial pressures after 1 hour, 6 hours, 12 hours and then every 24 hours after enrolment. <br/ ><br>2.To compare the intubation free ICU stay of patients. <br/ ><br>3.To compare percentage of patients who required non-invasive ventilation.Timepoint: 28 days