Compare the Efficacy of Acupuncture Therapy and Carbamazepine Oral Dosage in Patients With Carpal Tunnel Syndrome by Multiple Excitability Test

Not Applicable

• Conditions: Carpal Tunnel Syndrome; Multiple Excitability Test
• Interventions: Procedure: Acupuncture; Drug: Carbamazepine

• Registration Number: NCT00952432
• Lead Sponsor: Taipei Medical University WanFang Hospital

Brief Summary

The goal of the study is to utilize BCTQ(Boston Carpal Tunnel Questionnaire), VAS (Visual Analog Scale), NCS (Nerve Conduction Study), and MET(Multiple Excitability Test) to evaluate and compare the efficacy of Acupuncture Therapy and Carbamazepine in Patients with Carpal Tunnel Syndrome.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-05
• Study First Submitted: 2009-08-03
• Study First Submitted QC: 2009-08-04
• Study First Posted: 2009-08-06
• Status Verified: 2011-04
• Last Update Submitted: 2011-04-11
• Last Update Posted: 2011-04-12
• Primary Completion: 2011-05
• Study Completion: 2011-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Age greater than 20 years old
• outpatient or inpatient subject with numbness of arm, clinically met diagnostic criteria of AAEM(American association of Electrodiagnostic Medicine CTS task force), and proven to have distal motor neurological disorder through nerve Conduction Study (distal motor latency >4.6 msec, decreased SNAP < 12uV or prolonged median sensory distal latency (palm to wrist) > 2.5msec)。
• Willing to sign the Informed Consent form

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Exclusion Criteria

• subject with external hand injury or disformation
• subject with Polyneuritis or Cervical nerve root lesions
• Subject with peripheral hypertrophy, hypothyroidism, multiple myeloma, or amyloidosis
• Allergic to Carbamazepine or similar type of medicine
• inability to act independently, or in the opinion of the investigator, not suitable for the study
• In the opinion of the investigator, the subject requires surgical repair of the Carpal Tunnel Syndrome, or the symptoms will be worsen result in irreversible damage to the subject if not treated with surgical repair within 3 months.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
ACUPUNCTURE	Acupuncture	ACUPUNCTURE
MEDICATION	Carbamazepine	Carbamazepine

Primary Outcome Measures

Name	Time	Method
Use QtracW and NCS to evaluate the changes between pre-treatment and post-treatment in patients in both arms.	12 weeks

Secondary Outcome Measures

Name	Time	Method
use BCTQ to evaluate the efficacy of 2 arms at week 4 and at week 12.	12 weeks
use VAS to evaluate the efficacy of 2 arms at week 5, 8 and 12.	12 weeks
Use Quality of Life questionnaire to compare the efficacy of 2 arms at week 12.	12 weeks
Evaluate the safety of 2 arms during the study period	12 weeks

Trial Locations

Locations (1)

Taipei Medical University - Wan Fang Hospital; 🇨🇳 Taipei, Taiwan