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Carbamazepine

Generic Name
Carbamazepine
Brand Names
Carbatrol, Carnexiv, Epitol, Equetro, Tegretol
Drug Type
Small Molecule
Chemical Formula
C15H12N2O
CAS Number
298-46-4
Unique Ingredient Identifier
33CM23913M

Overview

Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, this drug is also given to control the symptoms of bipolar 1. Interestingly, carbamazepine was the first anticonvulsant used to treat individuals with bipolar disorder.

Background

Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, this drug is also given to control the symptoms of bipolar 1. Interestingly, carbamazepine was the first anticonvulsant used to treat individuals with bipolar disorder.

Indication

Carbamazepine is indicated for the treatment of epilepsy and pain associated with true trigeminal neuralgia. In particular, carbamazepine has shown efficacy in treating mixed seizures, partial seizures with complex symptoms, and generalized tonic-clonic seizures. Carbamazepine is also indicated for the treatment of manic episodes and mixed manic-depressive episodes caused by bipolar I disorder. Some off-label, unapproved uses of carbamazepine include the treatment of alcohol withdrawal syndrome and restless leg syndrome.

Associated Conditions

  • Acute Mania
  • Alcohol Withdrawal Syndrome
  • Complex Partial Seizure Disorder
  • Generalized Tonic-Clonic Seizures
  • Mixed manic depressive episode
  • Pain
  • Partial Seizures With Secondary Generalization
  • Restless Legs Syndrome (RLS)

FDA Approved Products

Tegretol
Manufacturer:Novartis Pharmaceuticals Corporation
Route:ORAL
Strength:200 mg in 1 1
Approved: 2018/11/07
NDC:0078-0509
CARBAMAZEPINE
Manufacturer:Golden State Medical Supply, Inc.
Route:ORAL
Strength:200 mg in 1 1
Approved: 2024/02/21
NDC:60429-032
Carbamazepine ER
Manufacturer:Sandoz Inc
Route:ORAL
Strength:400 mg in 1 1
Approved: 2019/11/12
NDC:0781-5988
Carbamazepine ER
Manufacturer:Sandoz Inc
Route:ORAL
Strength:200 mg in 1 1
Approved: 2019/11/12
NDC:0781-5987
Carbamazepine
Manufacturer:Bryant Ranch Prepack
Route:ORAL
Strength:200 mg in 1 1
Approved: 2021/12/21
NDC:71335-1730

Singapore Approved Products

APO-CARBAMAZEPINE TABLET 200 mg
Manufacturer:APOTEX INC
Form:TABLET
Strength:200 mg
Online:Yes
Approved: 1991/04/08
Approval:SIN05735P
TEGRETOL CR 400 TABLET 400 mg
Manufacturer:NOVARTIS FARMA S P A, Mipharm S.p.A. (Primary and Secondary Packager)
Form:TABLET, FILM COATED
Strength:400 mg
Online:Yes
Approved: 1988/11/10
Approval:SIN02388P
TEGRETOL 200 TABLET 200 mg
Manufacturer:NOVARTIS FARMA S P A, Mipharm S.p.A (primary & secondary packaging)
Form:TABLET
Strength:200 mg
Online:Yes
Approved: 1988/04/26
Approval:SIN00352P
TEGRETOL CR 200 TABLET 200 mg
Manufacturer:NOVARTIS FARMA S P A, Mipharm S.p.A. (Primary and Secondary Packager)
Form:TABLET, FILM COATED
Strength:200 mg
Online:Yes
Approved: 1988/11/10
Approval:SIN02387P
Tegretol Oral Suspension 2%
Manufacturer:Delpharm Huningue S.A.S.
Form:SUSPENSION
Strength:2 g/100 ml
Online:Yes
Approved: 1988/04/28
Approval:SIN00510P

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