the Influence of General Anesthesia on Tumor Metastasis and Recurrence
- Conditions
- Tumor Recurrence and Metastasis
- Interventions
- Other: general anesthesia and local anesthesia
- Registration Number
- NCT02474511
- Lead Sponsor
- RenJi Hospital
- Brief Summary
The purpose of this study was to investigate whether general anesthesia will affect the postoperative recurrence and metastasis of malignant tumor.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
- ASA I - III Primary liver cancer tumor is single and diameter is less than 3 centimeter There is no major vascular invasion phenomenon, no lymph nodes or extrahepatic metastases The Child - Pugh belong to type A or type B
Exclusion Criteria
- Had a history of liver surgery (including radiofrequency ablation) Severe disease of heart, lung, kidney, the immune system INR > 1.5 or platelet count is less than 45000 cells/mm3 History of opioid addiction Metastatic liver tumors Not sure of primary liver cancer Don't agree to participate in this experiment
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description local anesthesia general anesthesia and local anesthesia In this group，the patient is received radiofrequency ablation under local anesthesia. general anesthesia general anesthesia and local anesthesia In this group，the patient is received radiofrequency ablation under general anesthesia.
- Primary Outcome Measures
Name Time Method Number of participants with tumor recurrence and metastasis 3 years Follow-up of patients with tumor recurrence and metastasis after Radiofrequency ablation to 3 years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Shanghai Renji Hospital
🇨🇳Shanghai, Shanghai, China