Optimum Diagnostic Testing for Glucocorticoid Induced Hyperglycaemia
Not Applicable
Recruiting
- Conditions
- Diabetes induced by GlucocorticoidsMetabolic and Endocrine - Diabetes
- Registration Number
- ACTRN12621001106820
- Lead Sponsor
- Associate Professor Morton Burt
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
1)Age greater than or equal to 18 years.
2)Prescribed greater than 4 mg of prednisolone per day for at least 3 months
Exclusion Criteria
1)Known diabetes
2)Transaminase LFT derangement (greater than 3 times the upper limit of normal)
3)Acute or chronic pancreatitis
4)Glycogen storage diseases
5)Pregnancy
6)Creatinine clearance less than 30 ml/min
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary endpoint is the difference in sensitivity between fasting glucose and random afternoon glucose to diagnose diabetes, as estimated by the area under their respective receiver operator characteristic curves. The diagnosis of diabetes will be defined by the current gold-standard, an oral glucose tolerance test.[ Baseline]
- Secondary Outcome Measures
Name Time Method o prespecified secondary outcomes[ No prespecified secondary outcomes ]