Assessment of the effect of aspirin on periapical inflammatio
Phase 3
Not yet recruiting
- Conditions
- Apical periodontitis.Chronic apical periodontitisK04.5
- Registration Number
- IRCT20191211045702N1
- Lead Sponsor
- Hamedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Patients with good general health
Patients aged 18-45 years
All single root, distal root of mandibular molars and palatal root of maxillary molars with periapical lesion of >5 mm in diameter
Tooth with no history of trauma and previous root canal treatment
Exclusion Criteria
Unable to isolate tooth
Presence of periodontal disease
Presence of systemic disease
History or presence of other infections
Specific physiological conditions
Oral ulcer
Smokers and alcoholics
Gastrointestinal problems
Treatment with any drug over the past week
Sensitivity to salicylates or other non-steroidal anti-inflammatory drugs
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Concentration of inflammatory mediator. Timepoint: At baseline and 7 days later. Method of measurement: Enzyme-linked immunosorbent kit.
- Secondary Outcome Measures
Name Time Method