Study of impact of dual chamber pacing on right atrial function.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- The changes in the right atrial morphometric and functional parameters after dual chamber pacemaker implantation.
Study Overview
Brief Summary
At the outset, we will obtain necessary approvals, including IRC (Institutional Review Committee), IEC (Institutional Ethics Committee) approval, and registration with CTRI (Clinical Trials Registry - India). Our study will focus on patients aged 18 years and above, who undergo dual chamber pacemaker implantation. Before the study, we will approach these patients and provide a detailed explanation of the research. Upon their understanding and agreement, informed consent will be obtained. Demographic details and clinical data and treatment receiving will be collected using proforma. Echocardiography will be done as a standard care in which RA size, RA area, RV wall thickness, RVOT diameter, TAPSE, IVC diameter and E/A ratio will be measured. Speckle-tracking echo will be done to measure RA strain, Strain rate and RV strain. Echocardiography will be done at 3 different dates. First echo will be done 1-2 days prior to pacemaker implantation. Second echo will be done 1-2 days after the pacemaker implantation and the third echo will be done after 1 month of procedure during follow-up. Patients with RV pacing of more than 40% will be included in this study. There will be no need for additional visits or follow-up in this study.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18.00 Year(s) to 99.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Individuals with dual chamber pacemaker Patient with RV pacing more than 40%.
Exclusion Criteria
- •Structural heart disease Previous DDDR Previous cardiac surgerires or interventions Dysfunctional pacemakers Presence of documented cardiac arrhythmias Known RV dysfunction.
Outcomes
Primary Outcomes
The changes in the right atrial morphometric and functional parameters after dual chamber pacemaker implantation.
Time Frame: RA structure and function will be assessed through echo on 1-2 days before , 1-2 days after and 1 month post pacemaker implantation.
Secondary Outcomes
- Right Ventriuclar dysfunction & its co relation with right atrial functional & morphometric parameters.(RV function will be assessed through echo on 1-2 days before, 1-2 days after & 1 month post pacemaker implantation.)
Investigators
DR Harshvardhan N M
MANIPAL ACADEMY OF HIGHER EDUCATION
