Record Voxel Rate Nonlinear Optical Microscope to Unravel Brain Connectome and Signaling

Recruiting

• Conditions: Brain Tumor; Brain Cancer

• Registration Number: NCT05943262
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-6-18
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Inclusion Criteria:<br><br> 1. Patients older than the age of 20 with diagnosis of brain tumor (both<br> newly-diagnosed or recurrent) who are suitable and willing to receive resection<br> surgery.<br><br>Exclusion Criteria:<br><br> 1. Patients who cannot give consent to participate in the study.<br><br> 2. The tumor samples failed to give a conclusive pathological diagnosis by standard<br> pathological workflow.<br><br> 3. Patients who only receives biopsy surgery rather than resection surgery.<br><br> 4. Significant post-irradiation effect or radiation necrosis reported in the<br> pathological examination.

Exclusion Criteria

Not provided

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Develop a standard whole-mount tissue processing protocol;Obtain images from H&E and IHC stained brain tumor tissues by nonlinear optical microscopy

Secondary Outcome Measures

Name	Time	Method
Distinguish between normal tissue and brain tumor and determine the extent and grade of the brain tumors