Exertional Rhabdomyolysis- Characterization of Prediction Tests for Return to Duty
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- creatine phosphokinase (CPK)
研究概览
简要总结
In order to determine norm values for skeleton muscle disassembly due to physical exertion in healthy and trained population, and developing a prediction test for approval for rhabdomyolysis injuries to return to duty, 50 healthy subjects will undergo a series of different physical tests.
详细描述
50 healthy civilians volunteers will be recruited for this study. Each subject will undergo the physical tests: anthropometric measurements, wingate test, VO2max test, step test and running on the anaerobic threshold, on separate days. Blood sample, lactic acid level (measured in blood drop - finger sting) and urine sample will be taken before and after every test.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •healthy civilians ages 18-
- •above average aerobic and anaerobic fitness.
- •Without heart, cardiovascular, metabolic or respiratory illnesses.
- •Without known medical illness or medication use that might endanger the participants.
排除标准
- •existence of any of undesired conditions detailed in the inclusion criteria.
- •the physician decision.
结局指标
主要结局
creatine phosphokinase (CPK)
时间窗: 5 experiment days for each subject
CPK is a marker for muscle damage assessed in blood test. blood sample will be taken before and after step test and running on the anaerobic threshold test.
oxygen consumption (VO2)
时间窗: 5 experiment days for each subject
VO2 will be monitored continuously using a metabolic system (ERGOTEST 680, ZAN, GERMANY ) during VO2max test, step test and running on the anaerobic threshold test.
次要结局
- lactic acid(5 experiment days for each subject)
- Myoglobin(5 experiment days for each subject)
- Heart rate(5 experiment days for each subject)