Effect of Treatment on Work Experience in Patients With Stage I-III Prostate Cancer

Completed

• Conditions: Stage III Prostate Cancer; Stage II Prostate Cancer; Prostate Adenocarcinoma; Stage I Prostate Cancer
• Interventions: Other: Interview; Other: Questionnaire Administration

• Registration Number: NCT03963739
• Lead Sponsor: Wake Forest University Health Sciences

Brief Summary

The objective of this study is to examine how adenocarcinoma of the prostate treatment differentially affects African American men's ability to work and to describe and compare changes in work ability (as measured through self-reported global work ability item) reported by African American and white adenocarcinoma of the prostate survivors before treatment and 6 months after treatment completion.

Detailed Description

This observational, longitudinal study will recruit approximately 255 patients through the Wake Forest National Cancer Institute Community Oncology Research Program (NCORP) Research Base (WF NCORP RB). The recruitment goal will be to have 160 participants who complete the interviewer-administered Structured Questionnaire at all three time points. All participants will be administered the first Structured Questionnaire prior to a prostatectomy or initiation of radiation therapy to treat adenocarcinoma of the prostate. Participants will also be administered Structured Questionnaires at three and six months after the prostatectomy or completion of radiation therapy. For most patients, the time between study enrollment and completion of participation will be approximately 6 - 10 months. Interviewer-administered Structured Questionnaires will address work ability, job characteristics, presence of symptoms associated with adenocarcinoma of the prostate treatment, and general background information.

Study Timeline

• Study First Submitted: 2019-05-21
• Study First Submitted QC: 2019-05-21
• Study First Posted: 2019-05-28
• Study Start: 2019-07-19
• Status Verified: 2025-03
• Primary Completion: 2025-03-25
• Study Completion: 2025-03-25
• Last Update Submitted: 2025-03-25
• Last Update Posted: 2025-03-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 255

Inclusion Criteria

• Male diagnosed with adenocarcinoma of the prostate, stage I, II, or III. Patient may have already received hormonal therapy or expect to receive hormonal therapy as treatment for adenocarcinoma of the prostate
• Scheduled to undergo prostatectomy or initiate radiation for primary curative treatment of adenocarcinoma of the prostate within 90 days of enrollment
• Self-identify as African American/black, non-Hispanic OR white, non-Hispanic; Participants are considered African American for recruitment purposes if they (1) identify solely as African American for race OR (2) identify as African American and white for race, but do not identify as also being of another race. Participants are considered white for recruitment purposes if they select white and no other race. (These identities are based on participant self-report during the screening process.)
• Eastern Cooperative Oncology Group (ECOG) score = 0 or 1
• Worked within the past 14 days prior to screening (no minimum number of hours required) OR (a) worked at some point between March 1, 2020 - March 14, 2020 and (b) subsequently lost job involuntarily due to COVID-19.
• Intends to be working 6 months from screening (if opportunity to work is available pending the COVID-19 pandemic considerations)
• Patient is willing to provide answers on the patient eligibility questionnaire regarding household income
• Age at time of screening is > or = 18
• Can speak and understand spoken English
• Ability to understand an informed consent document (even if only verbally) and willingness to agree to informed consent document
• Access to telephone or willingness to travel to National Cancer Institute (NCI) Community Oncology Research Program (NCORP) site for each of the three interviewer-administered structured questionnaires
• Able to hear sufficiently to understand a conversation determined by a simple test given at screening
• Has not previously had a prostatectomy, radiation therapy, or chemotherapy to treat adenocarcinoma of the prostate
• Not expected (at time of screening) to receive chemotherapy for primary treatment of adenocarcinoma of the prostate

Exclusion Criteria

• Patient has received therapy for any other cancer within last 3 years (except for non-melanoma skin cancer)
• Patient plans to receive therapy for any other cancer within the next year (except for non-melanoma skin cancer)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Race: Non-Hispanic White	Questionnaire Administration	Patients undergo an interview over 40-60 minutes at baseline and 3 and 6 months after treatment to describe and compare changes in ability to work and employment status/income.
Race: Non-Hispanic African American	Interview	Patients undergo an interview over 40-60 minutes at baseline and 3 and 6 months after treatment to describe and compare changes in ability to work and employment status/income.
Race: Non-Hispanic White	Interview	Patients undergo an interview over 40-60 minutes at baseline and 3 and 6 months after treatment to describe and compare changes in ability to work and employment status/income.
Income: Lower Income	Questionnaire Administration	Patients undergo an interview over 40-60 minutes at baseline and 3 and 6 months after treatment to describe and compare changes in ability to work and employment status/income.
Income: Higher Income	Interview	Patients undergo an interview over 40-60 minutes at baseline and 3 and 6 months after treatment to describe and compare changes in ability to work and employment status/income.
Race: Non-Hispanic African American	Questionnaire Administration	Patients undergo an interview over 40-60 minutes at baseline and 3 and 6 months after treatment to describe and compare changes in ability to work and employment status/income.
Income: Lower Income	Interview	Patients undergo an interview over 40-60 minutes at baseline and 3 and 6 months after treatment to describe and compare changes in ability to work and employment status/income.
Income: Higher Income	Questionnaire Administration	Patients undergo an interview over 40-60 minutes at baseline and 3 and 6 months after treatment to describe and compare changes in ability to work and employment status/income.

Primary Outcome Measures

Name	Time	Method
Change in work ability measured by Global Work Ability	Baseline up to 6 months after treatment completion	Calculate 95% confidence intervals around the work ability score and the change in the work ability score. A two group t-test will be used to compare changes in the work ability score by race (white, African American), followed by a general linear model to compare changes in work ability with adjustment for demographic, work environment, and other baseline characteristics.

Secondary Outcome Measures

Name	Time	Method
Trajectory of change in work ability at 3 months measured by Global Work Ability	Baseline up to 3 months after treatment completion	Measured by Global Work Ability. Quantify this change using means and 95% confidence intervals. In mixed models to account for the repeated measures over time, will model this change by race, income, and the interaction between race and income. Will also test for race by time and income by time interactions to compare the trajectories of change over time.
Trajectory of change in work ability at 6 months measured by Global Work Ability	Baseline up to 6 months after treatment completion	In mixed models to account for the repeated measures over time, will model this change by race, income, and the interaction between race and income. Will also test for race by time and income by time interactions to compare the trajectories of change over time.
Trajectory of change in work ability at 6 months measured by Work Limitations Questionnaire (WLQ)	Baseline up to 6 months after treatment completion	Quantify this change using means and 95% confidence intervals. In mixed models to account for the repeated measures over time, will model this change by race, income, and the interaction between race and income. Will also test for race by time and income by time interactions to compare the trajectories of change over time.
Trajectory of change in work ability at 6 months measured by employment status	Baseline up to 6 months after treatment completion	A random effects logistic regression model (if binary) or multinomial model (if more than 2 categories) for modeling employment status. Backwards model selection and AIC criteria will be utilized to identify the best model fit.
Difference between preferred and actual length of leave	Up to 6 months after treatment completion	Examine whether demographics, treatment, psychosocial and physical effects of treatment, and work environment factors impact (a) desired and (b) actual length of leave following treatment for adenocarcinoma of the prostate. Factors that are significant at an alpha level of 0.25 or less or have significant interactions will be entered into a general linear model.
Trajectory of change in work ability at 3 months measured by Work Limitations Questionnaire (WLQ)	From baseline to 3 months after treatment completion	Quantify this change using means and 95% confidence intervals. In mixed models to account for the repeated measures over time, will model this change by race, income, and the interaction between race and income. Will also test for race by time and income by time interactions to compare the trajectories of change over time.
Trajectory of change in work ability at 3 months measured by employment status	Baseline up to 3 months after treatment completion	A random effects logistic regression model (if binary) or multinomial model (if more than 2 categories) for modeling employment status. Backwards model selection and Akaike information criterion (AIC) criteria will be utilized to identify the best model fit.

Trial Locations

Locations (324)

Columbus Oncology and Hematology Associates Inc; 🇺🇸 Columbus, Ohio, United States

Riverside Methodist Hospital; 🇺🇸 Columbus, Ohio, United States

Columbus NCI Community Oncology Research Program; 🇺🇸 Columbus, Ohio, United States

Saint Elizabeth Regional Medical Center; 🇺🇸 Lincoln, Nebraska, United States

North Grove Medical Park; 🇺🇸 Spartanburg, South Carolina, United States

Bon Secours Maryview Medical Center; 🇺🇸 Portsmouth, Virginia, United States

Rocky Mountain Cancer Centers-Longmont; 🇺🇸 Longmont, Colorado, United States

Good Samaritan Regional Health Center; 🇺🇸 Mount Vernon, Illinois, United States

Carle Cancer Center; 🇺🇸 Urbana, Illinois, United States

Marshfield Medical Center - Weston; 🇺🇸 Weston, Wisconsin, United States

Illinois CancerCare-Eureka; 🇺🇸 Eureka, Illinois, United States

Munson Medical Center; 🇺🇸 Traverse City, Michigan, United States

Central Care Cancer Center - Bolivar; 🇺🇸 Bolivar, Missouri, United States

Trinity Regional Medical Center; 🇺🇸 Fort Dodge, Iowa, United States

Mercy Hospital; 🇺🇸 Coon Rapids, Minnesota, United States

Good Samaritan Hospital - Cincinnati; 🇺🇸 Cincinnati, Ohio, United States

Oncology Hematology Care Inc-Kenwood; 🇺🇸 Cincinnati, Ohio, United States

Bethesda North Hospital; 🇺🇸 Cincinnati, Ohio, United States

Abbott-Northwestern Hospital; 🇺🇸 Minneapolis, Minnesota, United States

Cancer Center at Saint Joseph's; 🇺🇸 Phoenix, Arizona, United States

Mercy Hospital Oklahoma City; 🇺🇸 Oklahoma City, Oklahoma, United States

Kaiser Permanente-Anaheim; 🇺🇸 Anaheim, California, United States

Kaiser Permanente West Los Angeles; 🇺🇸 Los Angeles, California, United States

Kaiser Permanente Los Angeles Medical Center; 🇺🇸 Los Angeles, California, United States

Mission Hope Medical Oncology - Arroyo Grande; 🇺🇸 Arroyo Grande, California, United States

Pali Momi Medical Center; 🇺🇸 'Aiea, Hawaii, United States

Penrose-Saint Francis Healthcare; 🇺🇸 Colorado Springs, Colorado, United States

Kaiser Permanente-Irvine; 🇺🇸 Irvine, California, United States

Kaiser Permanente-Fontana; 🇺🇸 Fontana, California, United States

Queen's Cancer Center - Pearlridge; 🇺🇸 'Aiea, Hawaii, United States

Mercy Hospital Fort Smith; 🇺🇸 Fort Smith, Arkansas, United States

Mission Hope Medical Oncology - Santa Maria; 🇺🇸 Santa Maria, California, United States

Beebe Medical Center; 🇺🇸 Lewes, Delaware, United States

Southwest Oncology PC; 🇺🇸 Durango, Colorado, United States

Island Urology-Hilo; 🇺🇸 Hilo, Hawaii, United States

The Queen's Medical Center - West Oahu; 🇺🇸 'Ewa Beach, Hawaii, United States

Rocky Mountain Cancer Centers-Penrose; 🇺🇸 Colorado Springs, Colorado, United States

Beebe South Coastal Health Campus; 🇺🇸 Frankford, Delaware, United States

Littleton Adventist Hospital; 🇺🇸 Littleton, Colorado, United States

Hawaii Cancer Care - Westridge; 🇺🇸 'Aiea, Hawaii, United States

Delaware Clinical and Laboratory Physicians PA; 🇺🇸 Newark, Delaware, United States

Christiana Care Health System-Christiana Hospital; 🇺🇸 Newark, Delaware, United States

Helen F Graham Cancer Center; 🇺🇸 Newark, Delaware, United States

The Cancer Center of Hawaii-Pali Momi; 🇺🇸 'Aiea, Hawaii, United States

Longmont United Hospital; 🇺🇸 Longmont, Colorado, United States

Saint Mary Corwin Medical Center; 🇺🇸 Pueblo, Colorado, United States

Decatur Memorial Hospital; 🇺🇸 Decatur, Illinois, United States

Crossroads Cancer Center; 🇺🇸 Effingham, Illinois, United States

Castle Medical Center; 🇺🇸 Kailua, Hawaii, United States

Illinois CancerCare-Canton; 🇺🇸 Canton, Illinois, United States

Illinois CancerCare-Bloomington; 🇺🇸 Bloomington, Illinois, United States

SIH Cancer Institute; 🇺🇸 Carterville, Illinois, United States

John H Stroger Jr Hospital of Cook County; 🇺🇸 Chicago, Illinois, United States

Memorial Hospital of Carbondale; 🇺🇸 Carbondale, Illinois, United States

Illinois CancerCare-Carthage; 🇺🇸 Carthage, Illinois, United States

Heartland Cancer Research NCORP; 🇺🇸 Decatur, Illinois, United States

Illinois CancerCare-Dixon; 🇺🇸 Dixon, Illinois, United States

Illinois CancerCare-Galesburg; 🇺🇸 Galesburg, Illinois, United States

Carle Physician Group-Effingham; 🇺🇸 Effingham, Illinois, United States

Illinois CancerCare-Macomb; 🇺🇸 Macomb, Illinois, United States

Illinois CancerCare-Princeton; 🇺🇸 Princeton, Illinois, United States

OSF Saint Francis Radiation Oncology at Pekin; 🇺🇸 Pekin, Illinois, United States

Cancer Care Center of O'Fallon; 🇺🇸 O'Fallon, Illinois, United States

Illinois CancerCare-Peoria; 🇺🇸 Peoria, Illinois, United States

Valley Radiation Oncology; 🇺🇸 Peru, Illinois, United States

Saint Luke's Hospital; 🇺🇸 Cedar Rapids, Iowa, United States

Saint Anthony Regional Hospital; 🇺🇸 Carroll, Iowa, United States

Saint Joseph London; 🇺🇸 London, Kentucky, United States

Flaget Memorial Hospital; 🇺🇸 Bardstown, Kentucky, United States

Springfield Memorial Hospital; 🇺🇸 Springfield, Illinois, United States

Illinois CancerCare-Peru; 🇺🇸 Peru, Illinois, United States

Medical Oncology and Hematology Associates-West Des Moines; 🇺🇸 Clive, Iowa, United States

Central Care Cancer Center - Garden City; 🇺🇸 Garden City, Kansas, United States

Central Care Cancer Center - Great Bend; 🇺🇸 Great Bend, Kansas, United States

Commonwealth Cancer Center-Corbin; 🇺🇸 Corbin, Kentucky, United States

Our Lady of the Lake Physicians Group - Medical Oncology; 🇺🇸 Baton Rouge, Louisiana, United States

Mercy Medical Center-West Lakes; 🇺🇸 West Des Moines, Iowa, United States

Bronson Battle Creek; 🇺🇸 Battle Creek, Michigan, United States

LSU Health Baton Rouge-North Clinic; 🇺🇸 Baton Rouge, Louisiana, United States

Terrebonne General Medical Center; 🇺🇸 Houma, Louisiana, United States

Jewish Hospital Medical Center South; 🇺🇸 Shepherdsville, Kentucky, United States

Mary Bird Perkins Cancer Center - Houma; 🇺🇸 Houma, Louisiana, United States

Our Lady of the Lake Physician Group; 🇺🇸 Baton Rouge, Louisiana, United States

Our Lady of the Lake Medical Oncology; 🇺🇸 Baton Rouge, Louisiana, United States

West Michigan Cancer Center; 🇺🇸 Kalamazoo, Michigan, United States

Ascension Borgess Cancer Center; 🇺🇸 Oshtemo, Michigan, United States

Marie Yeager Cancer Center; 🇺🇸 Saint Joseph, Michigan, United States

Spectrum Health Reed City Hospital; 🇺🇸 Reed City, Michigan, United States

Monticello Cancer Center; 🇺🇸 Monticello, Minnesota, United States

Heartland Regional Medical Center; 🇺🇸 Saint Joseph, Missouri, United States

Health Partners Inc; 🇺🇸 Minneapolis, Minnesota, United States

Saint Louis Cancer and Breast Institute-Ballwin; 🇺🇸 Ballwin, Missouri, United States

Fairview Lakes Medical Center; 🇺🇸 Wyoming, Minnesota, United States

New Ulm Medical Center; 🇺🇸 New Ulm, Minnesota, United States

Minnesota Oncology - Burnsville; 🇺🇸 Burnsville, Minnesota, United States

Cambridge Medical Center; 🇺🇸 Cambridge, Minnesota, United States

Hennepin County Medical Center; 🇺🇸 Minneapolis, Minnesota, United States

Minnesota Oncology Hematology PA-Maplewood; 🇺🇸 Maplewood, Minnesota, United States

Saint John's Hospital - Healtheast; 🇺🇸 Maplewood, Minnesota, United States

Ridgeview Medical Center; 🇺🇸 Waconia, Minnesota, United States

Minnesota Oncology Hematology PA-Woodbury; 🇺🇸 Woodbury, Minnesota, United States

Saint Francis Medical Center; 🇺🇸 Cape Girardeau, Missouri, United States

Cox Cancer Center Branson; 🇺🇸 Branson, Missouri, United States

Southeast Cancer Center; 🇺🇸 Cape Girardeau, Missouri, United States

CHI Health Good Samaritan; 🇺🇸 Kearney, Nebraska, United States

Delbert Day Cancer Institute at PCRMC; 🇺🇸 Rolla, Missouri, United States

Parkland Health Center - Farmington; 🇺🇸 Farmington, Missouri, United States

Capital Region Southwest Campus; 🇺🇸 Jefferson City, Missouri, United States

Mercy Clinic-Rolla-Cancer and Hematology; 🇺🇸 Rolla, Missouri, United States

Saint Louis Cancer and Breast Institute-South City; 🇺🇸 Saint Louis, Missouri, United States

Sanford South University Medical Center; 🇺🇸 Fargo, North Dakota, United States

Nash General Hospital; 🇺🇸 Rocky Mount, North Carolina, United States

Nebraska Cancer Specialists/Oncology Hematology West PC; 🇺🇸 Grand Island, Nebraska, United States

Saint Peter's University Hospital; 🇺🇸 New Brunswick, New Jersey, United States

Midlands Community Hospital; 🇺🇸 Papillion, Nebraska, United States

Wake Forest Baptist Health - Wilkes Medical Center; 🇺🇸 Wilkesboro, North Carolina, United States

Sanford Bismarck Medical Center; 🇺🇸 Bismarck, North Dakota, United States

Holy Name Hospital; 🇺🇸 Teaneck, New Jersey, United States

Columbus Oncology and Hematology Associates; 🇺🇸 Dublin, Ohio, United States

Kettering Medical Center; 🇺🇸 Kettering, Ohio, United States

Mount Carmel East Hospital; 🇺🇸 Columbus, Ohio, United States

TriHealth Cancer Institute-Anderson; 🇺🇸 Cincinnati, Ohio, United States

Miami Valley Hospital; 🇺🇸 Dayton, Ohio, United States

Blanchard Valley Hospital; 🇺🇸 Findlay, Ohio, United States

Central Ohio Breast and Endocrine Surgery; 🇺🇸 Gahanna, Ohio, United States

Grant Medical Center; 🇺🇸 Columbus, Ohio, United States

Doctors Hospital; 🇺🇸 Columbus, Ohio, United States

The Mark H Zangmeister Center; 🇺🇸 Columbus, Ohio, United States

Mount Carmel Health Center West; 🇺🇸 Columbus, Ohio, United States

Dayton Physicians LLC-Atrium; 🇺🇸 Franklin, Ohio, United States

Dayton Physicians LLC-Wayne; 🇺🇸 Greenville, Ohio, United States

Dayton NCI Community Oncology Research Program; 🇺🇸 Dayton, Ohio, United States

Delaware Health Center-Grady Cancer Center; 🇺🇸 Delaware, Ohio, United States

Armes Family Cancer Center; 🇺🇸 Findlay, Ohio, United States

Grady Memorial Hospital; 🇺🇸 Delaware, Ohio, United States

Atrium Medical Center-Middletown Regional Hospital; 🇺🇸 Franklin, Ohio, United States

Dayton Physician LLC-Miami Valley Hospital North; 🇺🇸 Dayton, Ohio, United States

Wayne Hospital; 🇺🇸 Greenville, Ohio, United States

Dublin Methodist Hospital; 🇺🇸 Dublin, Ohio, United States

Orion Cancer Care; 🇺🇸 Findlay, Ohio, United States

Fairfield Medical Center; 🇺🇸 Lancaster, Ohio, United States

Newark Radiation Oncology; 🇺🇸 Newark, Ohio, United States

Mercy Health - Saint Vincent Hospital; 🇺🇸 Toledo, Ohio, United States

Saint Rita's Medical Center; 🇺🇸 Lima, Ohio, United States

Mercy Health Sylvania Radiation Oncology Center; 🇺🇸 Toledo, Ohio, United States

Springfield Regional Cancer Center; 🇺🇸 Springfield, Ohio, United States

Springfield Regional Medical Center; 🇺🇸 Springfield, Ohio, United States

Upper Valley Medical Center; 🇺🇸 Troy, Ohio, United States

Saint Elizabeth Youngstown Hospital; 🇺🇸 Youngstown, Ohio, United States

VCU Massey Cancer Center at Hanover Medical Park; 🇺🇸 Mechanicsville, Virginia, United States

Bon Secours Saint Francis Medical Center; 🇺🇸 Midlothian, Virginia, United States

Highline Medical Center-Main Campus; 🇺🇸 Burien, Washington, United States

Bon Secours Health Center at Harbour View; 🇺🇸 Suffolk, Virginia, United States

Saint Elizabeth Hospital; 🇺🇸 Enumclaw, Washington, United States

Gundersen Lutheran Medical Center; 🇺🇸 La Crosse, Wisconsin, United States

Marshfield Clinic-Minocqua Center; 🇺🇸 Minocqua, Wisconsin, United States

FHP Health Center-Guam; 🇬🇺 Tamuning, Guam

Porter Adventist Hospital; 🇺🇸 Denver, Colorado, United States

Mercy Hospital Saint Louis; 🇺🇸 Saint Louis, Missouri, United States

Wilcox Memorial Hospital and Kauai Medical Clinic; 🇺🇸 Lihue, Hawaii, United States

Park Nicollet Clinic - Saint Louis Park; 🇺🇸 Saint Louis Park, Minnesota, United States

Fairview Northland Medical Center; 🇺🇸 Princeton, Minnesota, United States

Rice Memorial Hospital; 🇺🇸 Willmar, Minnesota, United States

Medical Oncology Hematology Consultants PA; 🇺🇸 Newark, Delaware, United States

Louisiana Hematology Oncology Associates LLC; 🇺🇸 Baton Rouge, Louisiana, United States

Louisiana Hematology Oncology Associates; 🇺🇸 Baton Rouge, Louisiana, United States

LSU Healthcare Network / Metairie Multi-Specialty Clinic; 🇺🇸 Metairie, Louisiana, United States

Greater Dayton Cancer Center; 🇺🇸 Kettering, Ohio, United States

Mount Carmel Grove City Hospital; 🇺🇸 Grove City, Ohio, United States

Carle on Vermilion; 🇺🇸 Danville, Illinois, United States

Alegent Health Mercy Hospital; 🇺🇸 Council Bluffs, Iowa, United States

Cancer Care Specialists of Illinois - Decatur; 🇺🇸 Decatur, Illinois, United States

Alegent Health Immanuel Medical Center; 🇺🇸 Omaha, Nebraska, United States

Alegent Health Bergan Mercy Medical Center; 🇺🇸 Omaha, Nebraska, United States

Wake Forest University Health Sciences; 🇺🇸 Winston-Salem, North Carolina, United States

Alegent Health Lakeside Hospital; 🇺🇸 Omaha, Nebraska, United States

Creighton University Medical Center; 🇺🇸 Omaha, Nebraska, United States

Saint Francis Cancer Center; 🇺🇸 Greenville, South Carolina, United States

Kaiser Permanente-Ontario; 🇺🇸 Ontario, California, United States

Mercy Medical Center; 🇺🇸 Durango, Colorado, United States

Illinois CancerCare - Washington; 🇺🇸 Washington, Illinois, United States

Western Illinois Cancer Treatment Center; 🇺🇸 Galesburg, Illinois, United States

Centralia Oncology Clinic; 🇺🇸 Centralia, Illinois, United States

Carle Physician Group-Mattoon/Charleston; 🇺🇸 Mattoon, Illinois, United States

Illinois CancerCare-Ottawa Clinic; 🇺🇸 Ottawa, Illinois, United States

OSF Saint Francis Radiation Oncology at Peoria Cancer Center; 🇺🇸 Peoria, Illinois, United States

Illinois CancerCare-Pekin; 🇺🇸 Pekin, Illinois, United States

Methodist Medical Center of Illinois; 🇺🇸 Peoria, Illinois, United States

OSF Saint Francis Medical Center; 🇺🇸 Peoria, Illinois, United States

Memorial Medical Center; 🇺🇸 Springfield, Illinois, United States

Springfield Clinic; 🇺🇸 Springfield, Illinois, United States

Reid Health; 🇺🇸 Richmond, Indiana, United States

The Carle Foundation Hospital; 🇺🇸 Urbana, Illinois, United States

Physicians' Clinic of Iowa PC; 🇺🇸 Cedar Rapids, Iowa, United States

Saint Ann's Hospital; 🇺🇸 Westerville, Ohio, United States

Mary Bird Perkins Cancer Center; 🇺🇸 Baton Rouge, Louisiana, United States

Mercy Cancer Center-West Lakes; 🇺🇸 Clive, Iowa, United States

Methodist West Hospital; 🇺🇸 West Des Moines, Iowa, United States

Mary Bird Perkins Cancer Center - Covington; 🇺🇸 Covington, Louisiana, United States

Northshore Oncology Associates-Covington; 🇺🇸 Covington, Louisiana, United States

Regions Hospital; 🇺🇸 Saint Paul, Minnesota, United States

Cancer and Hematology Centers of Western Michigan - Norton Shores; 🇺🇸 Norton Shores, Michigan, United States

North Memorial Medical Health Center; 🇺🇸 Robbinsdale, Minnesota, United States

Gibbs Cancer Center-Gaffney; 🇺🇸 Gaffney, South Carolina, United States

Saint Francis Regional Medical Center; 🇺🇸 Shakopee, Minnesota, United States

Sanford Thief River Falls Medical Center; 🇺🇸 Thief River Falls, Minnesota, United States

Mercy Hospital South; 🇺🇸 Saint Louis, Missouri, United States

Knox Community Hospital; 🇺🇸 Mount Vernon, Ohio, United States

Genesis Healthcare System Cancer Care Center; 🇺🇸 Zanesville, Ohio, United States

Prisma Health Cancer Institute - Spartanburg; 🇺🇸 Boiling Springs, South Carolina, United States

South Carolina Cancer Specialists PC; 🇺🇸 Hilton Head Island, South Carolina, United States

CHI Saint Vincent Cancer Center Hot Springs; 🇺🇸 Hot Springs, Arkansas, United States

Kaiser Permanente-Baldwin Park; 🇺🇸 Baldwin Park, California, United States

Kaiser Permanente-Bellflower; 🇺🇸 Bellflower, California, United States

Christiana Care Health System-Wilmington Hospital; 🇺🇸 Wilmington, Delaware, United States

Parker Adventist Hospital; 🇺🇸 Parker, Colorado, United States

Saint Anthony Hospital; 🇺🇸 Lakewood, Colorado, United States

Beebe Health Campus; 🇺🇸 Rehoboth Beach, Delaware, United States

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler; 🇺🇸 Savannah, Georgia, United States

Illinois CancerCare-Kewanee Clinic; 🇺🇸 Kewanee, Illinois, United States

Southern Illinois University School of Medicine; 🇺🇸 Springfield, Illinois, United States

Greater Regional Medical Center; 🇺🇸 Creston, Iowa, United States

Cancer Research Consortium of West Michigan NCORP; 🇺🇸 Grand Rapids, Michigan, United States

Helen DeVos Children's Hospital at Spectrum Health; 🇺🇸 Grand Rapids, Michigan, United States

Mercy Health Saint Mary's; 🇺🇸 Grand Rapids, Michigan, United States

Spectrum Health at Butterworth Campus; 🇺🇸 Grand Rapids, Michigan, United States

Bronson Methodist Hospital; 🇺🇸 Kalamazoo, Michigan, United States

Borgess Medical Center; 🇺🇸 Kalamazoo, Michigan, United States

Mercy Health Mercy Campus; 🇺🇸 Muskegon, Michigan, United States

Lakeland Hospital Niles; 🇺🇸 Niles, Michigan, United States

Lakeland Medical Center Saint Joseph; 🇺🇸 Saint Joseph, Michigan, United States

Metro Health Hospital; 🇺🇸 Wyoming, Michigan, United States

Sanford Joe Lueken Cancer Center; 🇺🇸 Bemidji, Minnesota, United States

Fairview Ridges Hospital; 🇺🇸 Burnsville, Minnesota, United States

Unity Hospital; 🇺🇸 Fridley, Minnesota, United States

Fairview Southdale Hospital; 🇺🇸 Edina, Minnesota, United States

Fairview Clinics and Surgery Center Maple Grove; 🇺🇸 Maple Grove, Minnesota, United States

Lakeview Hospital; 🇺🇸 Stillwater, Minnesota, United States

United Hospital; 🇺🇸 Saint Paul, Minnesota, United States

Sainte Genevieve County Memorial Hospital; 🇺🇸 Sainte Genevieve, Missouri, United States

Missouri Baptist Sullivan Hospital; 🇺🇸 Sullivan, Missouri, United States

Mercy Hospital Washington; 🇺🇸 Washington, Missouri, United States

Missouri Baptist Outpatient Center-Sunset Hills; 🇺🇸 Sunset Hills, Missouri, United States

Wake Forest University at Clemmons; 🇺🇸 Clemmons, North Carolina, United States

Sanford Roger Maris Cancer Center; 🇺🇸 Fargo, North Dakota, United States

Strecker Cancer Center-Belpre; 🇺🇸 Belpre, Ohio, United States

Sanford Broadway Medical Center; 🇺🇸 Fargo, North Dakota, United States

Sanford Medical Center Fargo; 🇺🇸 Fargo, North Dakota, United States

Indu and Raj Soin Medical Center; 🇺🇸 Beavercreek, Ohio, United States

Saint Elizabeth Boardman Hospital; 🇺🇸 Boardman, Ohio, United States

Dayton Physicians LLC-Miami Valley South; 🇺🇸 Centerville, Ohio, United States

Miami Valley Hospital South; 🇺🇸 Centerville, Ohio, United States

Adena Regional Medical Center; 🇺🇸 Chillicothe, Ohio, United States

TriHealth Cancer Institute-Westside; 🇺🇸 Cincinnati, Ohio, United States

Miami Valley Hospital North; 🇺🇸 Dayton, Ohio, United States

OhioHealth Marion General Hospital; 🇺🇸 Marion, Ohio, United States

Licking Memorial Hospital; 🇺🇸 Newark, Ohio, United States

Marietta Memorial Hospital; 🇺🇸 Marietta, Ohio, United States

OhioHealth Mansfield Hospital; 🇺🇸 Mansfield, Ohio, United States

Mercy Health - Perrysburg Hospital; 🇺🇸 Perrysburg, Ohio, United States

Southern Ohio Medical Center; 🇺🇸 Portsmouth, Ohio, United States

Dayton Physicians LLC-Upper Valley; 🇺🇸 Troy, Ohio, United States

Mercy Health - Saint Anne Hospital; 🇺🇸 Toledo, Ohio, United States

Saint Joseph Warren Hospital; 🇺🇸 Warren, Ohio, United States

Saint Joseph's/Candler - Bluffton Campus; 🇺🇸 Bluffton, South Carolina, United States

Christiana Care Health System-Concord Health Center; 🇺🇸 Chadds Ford, Pennsylvania, United States

Prisma Health Cancer Institute - Easley; 🇺🇸 Easley, South Carolina, United States

Saint Francis Hospital; 🇺🇸 Federal Way, Washington, United States

Prisma Health Cancer Institute - Faris; 🇺🇸 Greenville, South Carolina, United States

Gibbs Cancer Center-Pelham; 🇺🇸 Greer, South Carolina, United States

Prisma Health Cancer Institute - Greer; 🇺🇸 Greer, South Carolina, United States

The Radiation Oncology Center-Hilton Head/Bluffton; 🇺🇸 Hilton Head Island, South Carolina, United States

Prisma Health Cancer Institute - Seneca; 🇺🇸 Seneca, South Carolina, United States

MGC Hematology Oncology-Union; 🇺🇸 Union, South Carolina, United States

Spartanburg Medical Center; 🇺🇸 Spartanburg, South Carolina, United States

Spartanburg Medical Center - Mary Black Campus; 🇺🇸 Spartanburg, South Carolina, United States

Bon Secours DePaul Medical Center; 🇺🇸 Norfolk, Virginia, United States

Bon Secours Westchester Emergency Center; 🇺🇸 Midlothian, Virginia, United States

Bon Secours Memorial Regional Medical Center; 🇺🇸 Mechanicsville, Virginia, United States

Saint Joseph Regional Cancer Center; 🇺🇸 Bryan, Texas, United States

Valley Medical Center; 🇺🇸 Renton, Washington, United States

Saint Michael Cancer Center; 🇺🇸 Bremerton, Washington, United States

Saint Clare Hospital; 🇺🇸 Lakewood, Washington, United States

Marshfield Medical Center-EC Cancer Center; 🇺🇸 Eau Claire, Wisconsin, United States

Franciscan Research Center-Northwest Medical Plaza; 🇺🇸 Tacoma, Washington, United States

Marshfield Medical Center-Rice Lake; 🇺🇸 Rice Lake, Wisconsin, United States

Marshfield Clinic Stevens Point Center; 🇺🇸 Stevens Point, Wisconsin, United States

Marshfield Medical Center-Marshfield; 🇺🇸 Marshfield, Wisconsin, United States

Westfields Hospital/Cancer Center of Western Wisconsin; 🇺🇸 New Richmond, Wisconsin, United States

Queen's Medical Center; 🇺🇸 Honolulu, Hawaii, United States

Queen's Cancer Center - Kuakini; 🇺🇸 Honolulu, Hawaii, United States

Hawaii Cancer Care Inc - Waterfront Plaza; 🇺🇸 Honolulu, Hawaii, United States

Island Urology; 🇺🇸 Honolulu, Hawaii, United States

Queen's Cancer Center - POB I; 🇺🇸 Honolulu, Hawaii, United States

Straub Clinic and Hospital; 🇺🇸 Honolulu, Hawaii, United States

University of Hawaii Cancer Center; 🇺🇸 Honolulu, Hawaii, United States

Hawaii Cancer Care Inc-Liliha; 🇺🇸 Honolulu, Hawaii, United States

Hawaii Diagnostic Radiology Services LLC; 🇺🇸 Honolulu, Hawaii, United States

Kuakini Medical Center; 🇺🇸 Honolulu, Hawaii, United States

The Cancer Center of Hawaii-Liliha; 🇺🇸 Honolulu, Hawaii, United States

Kapiolani Medical Center for Women and Children; 🇺🇸 Honolulu, Hawaii, United States

Jewish Hospital; 🇺🇸 Louisville, Kentucky, United States

Saints Mary and Elizabeth Hospital; 🇺🇸 Louisville, Kentucky, United States

UofL Health Medical Center Northeast; 🇺🇸 Louisville, Kentucky, United States

Louisiana State University Health Science Center; 🇺🇸 New Orleans, Louisiana, United States

Bon Secours Cancer Institute at Reynolds Crossing; 🇺🇸 Richmond, Virginia, United States

Medical University of South Carolina; 🇺🇸 Charleston, South Carolina, United States

VCU Massey Cancer Center at Stony Point; 🇺🇸 Richmond, Virginia, United States

Virginia Commonwealth University/Massey Cancer Center; 🇺🇸 Richmond, Virginia, United States

Bon Secours Saint Mary's Hospital; 🇺🇸 Richmond, Virginia, United States

Iowa Methodist Medical Center; 🇺🇸 Des Moines, Iowa, United States

Iowa-Wide Oncology Research Coalition NCORP; 🇺🇸 Des Moines, Iowa, United States

Medical Oncology and Hematology Associates-Des Moines; 🇺🇸 Des Moines, Iowa, United States

Broadlawns Medical Center; 🇺🇸 Des Moines, Iowa, United States

Medical Oncology and Hematology Associates-Laurel; 🇺🇸 Des Moines, Iowa, United States

Mercy Medical Center - Des Moines; 🇺🇸 Des Moines, Iowa, United States

Iowa Lutheran Hospital; 🇺🇸 Des Moines, Iowa, United States

Saint Joseph Radiation Oncology Resource Center; 🇺🇸 Lexington, Kentucky, United States

Saint Joseph Hospital East; 🇺🇸 Lexington, Kentucky, United States

Prisma Health Cancer Institute - Eastside; 🇺🇸 Greenville, South Carolina, United States

Prisma Health Cancer Institute - Butternut; 🇺🇸 Greenville, South Carolina, United States

Prisma Health Greenville Memorial Hospital; 🇺🇸 Greenville, South Carolina, United States

Southpointe-Sanford Medical Center Fargo; 🇺🇸 Fargo, North Dakota, United States

OSF Saint Anthony's Health Center; 🇺🇸 Alton, Illinois, United States