The effect of anti-inflammatory drug and acetaminophen on postpartum hypertensio

Phase 2

Recruiting

• Conditions: Postpartum hypertension.; Eclampsia in the puerperium; O15.2

• Registration Number: IRCT20210823052269N1
• Lead Sponsor: Arak University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 January 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 110

Inclusion Criteria

Cesarean candidate patients
No chronic liver, kidney, hemorrhagic disorders
No history of allergy to nonsteroidal anti-inflammatory drugs and acetaminophen
Severe preeclampsia or preeclampsia added to chronic hypertension with severe symptoms

Exclusion Criteria

Increase in liver enzyme levels higher than 200 mg / dL
Increase in serum creatinine higher than 2 mg / d

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary variable: Duration of high blood pressure. Timepoint: Measure blood pressure for 24 hours every hour and then every 4 hours. Method of measurement: Mercury sphygmomanometer.;Primary variable: Frequency of need to use short acting antihypertensive drugs. Timepoint: Measure blood pressure for 24 hours every hour and then every 4 hours. Method of measurement: Counting.

Secondary Outcome Measures

Name	Time	Method
Frequency of need to use short-acting antihypertensive drugs to control sudden hypertension in both groups receiving acetaminophen and nonsteroidal anti-inflammatory drugs. Timepoint: At the beginning of the study (before the intervention), for 24 hours every hour and then every 4 hours. Method of measurement: Counting.