Effect of nonsteroidal anti-inflammatory drugs in the management of postoperative pain after cardiac surgery: A multicentre, randomised, placebo-controlled trial
Phase 1
- Conditions
- Postoperative pain after cardiac surgeryTherapeutic area: Diseases [C] - Cardiovascular Diseases [C14]
- Registration Number
- CTIS2023-506299-28-00
- Lead Sponsor
- Centre Hospitalier Universitaire Amiens Picardie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 238
Inclusion Criteria
Patient aged 18 or older admitted for elective cardiac surgery under extracorporeal circulation, Signed informed consent
Exclusion Criteria
Thoracotomy approach, 2 Minimally invasive approach, Renal replacement therapy within the last 90 days, Depression with long-term treatment, History of gastrointestinal ulcer, Chronic use of NSAIDs before the operation, Opioid dependence or chronic opioid medication, Contraindications to the use of NSAIDs, Emergency surgery, Acute infectious endocarditis, AIDS with a CD4 count <200/mm3, Autoimmune disorder, Advanced chronic kidney disease (CKD 4 or 5)
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method