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Impact of prescribing nonsteroidal anti-inflammatory drugs in pleurodesis surgery after pneumothorax: a prospective randomized controlled double-blind multicenter noninferiority study

Phase 1
Conditions
pleurodesis surgery for cure of pneumothorax
Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]
Registration Number
CTIS2024-511226-32-00
Lead Sponsor
Centre Hospitalier Universitaire Amiens Picardie
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
358
Inclusion Criteria

Pneumothorax for video-exclusive surgical indication With or without minor lung resection (atypical resection), Age > or = 18 years old, Written or oral informed consent to participate in the study., Affiliation to a social security scheme, Highly effective contraception for women of childbearing age (combined hormonal contraception (estrogen and progesterone) combined with ovulation inhibition (oral, intra-vaginal, transdermal), hormonal contraception (progesterone only) combined with ovulation inhibition (oral, injectable, implantable), intrauterine device, hormone-releasing intrauterine system, bilateral fallopian tube occlusion, vasectomized partner, sexual abstinence, etc.). )

Exclusion Criteria

Minor, Patient under guardianship, curatorship or deprived of liberty, patient who refuses to participate in the study, Contraindication to the use of NSAIDs, Contraindications to the use of TRAMADOL, Curative anticoagulation, Contraindications to the use of NEFOPAM, Contraindications to the use of PARACETAMOL, Contraindications to the use of SODIUM CHLORIDE, Lactose intolerance, Hemopneumothorax, Purulent pleurisy, Polytraumatized, Pregnant, parturient or breastfeeding patient

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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