Can certain anaesthesia medications & techniques provide additional benefits after cancer surgery apart from pain relief and speed of recovery from that surgery (LIPO trial - Lignocaine infusion given peri-operatively)

Phase 4

• Conditions: on-metastatic cancers in patients undergoing primary cancer surgery; Non-metastatic cancers in patients undergoing primary cancer surgery; Cancer - Any cancer; Anaesthesiology - Anaesthetics

• Registration Number: ACTRN12611001005943
• Lead Sponsor: Palmerston North Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-09-20
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 600

Inclusion Criteria

Non metastatic cancer requiring primary surgery:
Colectomy, nephrectomy, prostatectomy, hysterectomy, melanoma excision, mastectomy, cystectomy

Exclusion Criteria

Metastases
ASA 4 and above
Diabetes
Concurrent pre-operative opioid analgesic use
Anti arrythmic drugs, arrythmogenic conditions
Hepatic or renal impairment
Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Tumour recurrence. Clinical assessments and relevant biochemical markers specific to each cancer type.[1 year, 3 years]

Secondary Outcome Measures

Name	Time	Method
Mortality. Death register investigation, phone calls to prompt clinical assessment by surgeons, note retrieval to determine surgical outcome. Biochemical markers relevant to the specific cancer type.[1 year, 3 years];Quality of hospital stay, including pain, DVT, and other miscellanous surgical complications. Recording of pain medication used, pain scores, length of stay, possible complications (free format)[Up to 1 week post operation]