A comparison of depth of muscle relaxation to improve performance of percutaneous ablation of liver tumours

Phase 3

Recruiting

• Conditions: iver tumour (primary or secondary); Liver tumour (primary or secondary); Anaesthesiology - Anaesthetics; Cancer - Liver

• Registration Number: ACTRN12615000838516
• Lead Sponsor: niversity Malaya

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-08-11
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

ASA 1 to 3
-Age between 18 to 75 years old
-Confirmed diagnosis of primary or secondary liver tumours and planned for elective percutaneous ablation by primary team and radiologist.

Exclusion Criteria

1.Refusal to participate in this study by patient or the legal representative
2.Any contraindications to the RFA procedure
3.Any contraindications to general anaesthesia
4.Any contraindications to any of the drugs used such as
i)severe renal impairment for rocuronium and sugammadex
ii)allergy
5.Pregnant or breastfeeding patients

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the difference in the mean of liver excursion (in mm) during the procedure between deep neuromuscular blockade (DMB) in Group 1 and moderate neuromuscular blockade (MMB) in Group 2.<br>Amplitude of liver excursion will be measured (in milimetres) during baseline CT and post-procedure multiphasic contrast-enhanced CT and recorded. The number and site of lesions will also be recorded in the data collecting form to judge the difficulty of performing the procedure due to anatomical constraints.[CT scans at baseline, during the RFA procedure and immediately following its completion.];Evaluating the ease of performing the RFA in liver tumours on a 5-point scale by the interventional radiologist.[At the end of procedure]