Early Exposure to Lead and Adult Antisocial Outcomes

Completed

• Conditions: Lead Poisoning

• Registration Number: NCT00285610
• Lead Sponsor: National Institute of Environmental Health Sciences (NIEHS)

Brief Summary

Prior research indicates a link between early lead exposure and risk for delinquent behavior. In this study, we follow a large birth cohort from the Cincinnati Lead Study into early adulthood to determine whether this increased risk persists. Outcome measures include official arrest records, diagnoses of Substance Abuse Disorder and Antisocial Personality Disorder, self-report of delinquent behavior, and a psychopathy scale. Predictors include pre-natal and post-natal blood lead levels. Multivariate statistical methods will control for potential confounders/covariates.

Detailed Description

Not available

Study Timeline

• Study Start: 2001-11
• Study First Submitted: 2006-02-01
• Study First Submitted QC: 2006-02-01
• Study First Posted: 2006-02-02
• Primary Completion: 2006-10
• Study Completion: 2006-10
• Status Verified: 2014-11
• Last Update Submitted: 2014-11-17
• Last Update Posted: 2014-11-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 225

Inclusion Criteria

(1) Part of original CLS birth cohort -

Exclusion Criteria

(1) Moved out of geographic area

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Lead Exposure and Antisocial Behavior	Prenatal (1-2 trimester) and postnatal on a quarterly and bi-annual basis (until 6.5 years)

Trial Locations

Locations (1)

Children's Hospital Medical Center; 🇺🇸 Cincinnati, Ohio, United States