Consistency of Carotid Doppler Blood Flow and Thermodilution Technique

Not Applicable

Recruiting

• Conditions: Cardiac Surgery
• Interventions: Behavioral: passive leg raising; Drug: Dobutamine

• Registration Number: NCT05944146
• Lead Sponsor: Shanghai Zhongshan Hospital

Brief Summary

Currently, the gold standard method to estimate CO is the thermodilution technique, pulmonary artery catheter (PAC) and PiCCO system included, however, the invasiveness and complexity of the thermodilution technique have limited their usefulness in many clinical scenarios. By measuring the carotid blood flow, continuous carotid doppler technique has been reported to noninvasively estimate cardiac output (CO) and other parameters related to cardiac contractility and fluid status in various cardiovascular disorders. However, to the best of our knowledge, few study has been reported to evaluate the consistency of this technique in cardiac surgery patients. The aim of this study is to evaluate the tracking ability of CO changes measured by continuous carotid doppler technique in cardiac surgery patients, use the thermodilution technique as the referenced.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-05-31
• Status Verified: 2023-07
• Study First Submitted: 2023-07-05
• Study First Submitted QC: 2023-07-12
• Last Update Submitted: 2023-07-12
• Study First Posted: 2023-07-13
• Last Update Posted: 2023-07-13
• Primary Completion: 2026-12-31
• Study Completion: 2026-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• adult cardiac surgery patients
• with thermodilution technique monitoring
• mechanical ventilation

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Exclusion Criteria

• life threatening arrhythmia
• severe valve regurgitation
• left ventricular ejection fraction less than 30%
• patients with mechanical circulatory support

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
cardiac surgery patients with thermodilution technique monitoring	passive leg raising	-
cardiac surgery patients with thermodilution technique monitoring	Dobutamine	-

Primary Outcome Measures

Name	Time	Method
cardiac output by thermodilution method	30 minutes after dobutamine infusion	measuring cardiac output using thermodilution method
cardiac output by continuous carotid doppler blood flow	30 minutes after dobutamine infusion	measuring cardiac output using continuous carotid doppler blood flow

Trial Locations

Locations (1)

Zhongshan hospital Fudan University; 🇨🇳 Shanghai, Shanghai, China