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临床试验/NCT05944146
NCT05944146招募中不适用

The Consistency of Tracking Changes of Cardiac Output by Carotid Doppler Blood Flow and Thermodilution Technique in Cardiac Surgery Patients

Shanghai Zhongshan Hospital1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2023年5月31日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
200
试验地点
1
主要终点
cardiac output by thermodilution method

研究概览

简要总结

Currently, the gold standard method to estimate CO is the thermodilution technique, pulmonary artery catheter (PAC) and PiCCO system included, however, the invasiveness and complexity of the thermodilution technique have limited their usefulness in many clinical scenarios. By measuring the carotid blood flow, continuous carotid doppler technique has been reported to noninvasively estimate cardiac output (CO) and other parameters related to cardiac contractility and fluid status in various cardiovascular disorders. However, to the best of our knowledge, few study has been reported to evaluate the consistency of this technique in cardiac surgery patients. The aim of this study is to evaluate the tracking ability of CO changes measured by continuous carotid doppler technique in cardiac surgery patients, use the thermodilution technique as the referenced.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • adult cardiac surgery patients
  • with thermodilution technique monitoring
  • mechanical ventilation

排除标准

  • life threatening arrhythmia
  • severe valve regurgitation
  • left ventricular ejection fraction less than 30%
  • patients with mechanical circulatory support

研究组 & 干预措施

cardiac surgery patients with thermodilution technique monitoring

Experimental

干预措施: passive leg raising (Behavioral)

cardiac surgery patients with thermodilution technique monitoring

Experimental

干预措施: Dobutamine (Drug)

结局指标

主要结局

cardiac output by thermodilution method

时间窗: 30 minutes after dobutamine infusion

measuring cardiac output using thermodilution method

cardiac output by continuous carotid doppler blood flow

时间窗: 30 minutes after dobutamine infusion

measuring cardiac output using continuous carotid doppler blood flow

次要结局

未报告次要终点

研究者

发起方
Shanghai Zhongshan Hospital
申办方类型
Other
责任方
Sponsor

研究点 (1)

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