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Clinical Trials/NCT05944146
NCT05944146
Recruiting
Not Applicable

The Consistency of Tracking Changes of Cardiac Output by Carotid Doppler Blood Flow and Thermodilution Technique in Cardiac Surgery Patients

Shanghai Zhongshan Hospital1 site in 1 country200 target enrollmentMay 31, 2023

Overview

Phase
Not Applicable
Intervention
passive leg raising
Conditions
Cardiac Surgery
Sponsor
Shanghai Zhongshan Hospital
Enrollment
200
Locations
1
Primary Endpoint
cardiac output by thermodilution method
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

Currently, the gold standard method to estimate CO is the thermodilution technique, pulmonary artery catheter (PAC) and PiCCO system included, however, the invasiveness and complexity of the thermodilution technique have limited their usefulness in many clinical scenarios. By measuring the carotid blood flow, continuous carotid doppler technique has been reported to noninvasively estimate cardiac output (CO) and other parameters related to cardiac contractility and fluid status in various cardiovascular disorders. However, to the best of our knowledge, few study has been reported to evaluate the consistency of this technique in cardiac surgery patients. The aim of this study is to evaluate the tracking ability of CO changes measured by continuous carotid doppler technique in cardiac surgery patients, use the thermodilution technique as the referenced.

Registry
clinicaltrials.gov
Start Date
May 31, 2023
End Date
December 31, 2026
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Shanghai Zhongshan Hospital
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • adult cardiac surgery patients
  • with thermodilution technique monitoring
  • mechanical ventilation

Exclusion Criteria

  • life threatening arrhythmia
  • severe valve regurgitation
  • left ventricular ejection fraction less than 30%
  • patients with mechanical circulatory support

Arms & Interventions

cardiac surgery patients with thermodilution technique monitoring

Intervention: passive leg raising

cardiac surgery patients with thermodilution technique monitoring

Intervention: Dobutamine

Outcomes

Primary Outcomes

cardiac output by thermodilution method

Time Frame: 30 minutes after dobutamine infusion

measuring cardiac output using thermodilution method

cardiac output by continuous carotid doppler blood flow

Time Frame: 30 minutes after dobutamine infusion

measuring cardiac output using continuous carotid doppler blood flow

Study Sites (1)

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