The Consistency of Cardiac Output Measured by Electrical Cardiometry and Pulmonary Artery Catheter in Cardiac Surgery Patients With Pulmonary Arterial Hypertension or Right Heart Dysfunction
Overview
- Phase
- Not Applicable
- Intervention
- passive leg raising
- Conditions
- Pulmonary Arterial Hypertension
- Sponsor
- Shanghai Zhongshan Hospital
- Enrollment
- 199
- Locations
- 1
- Primary Endpoint
- cardiac output by pulmonary artery catheter
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
Currently, the gold standard method to estimate CO in patients with PAH or RV dysfunction is pulmonary artery catheter (PAC), however, the invasiveness and complexity of PAC has limited its usefulness in many clinical scenarios. By measuring the thoracic electrical bioimpedance, electrical cardiometry (EC) technique has been reported to noninvasively estimate cardiac output (CO) and other parameters related to cardiac contractility and fluid status in various cardiovascular disorders. However, in patients with pulmonary arterial hypertension (PAH) and/or right ventricular (RV) dysfunction, few study has been reported. The aim of this study is to evaluate the agreement between CO measured by PAC as the referenced method and CO measured by EC technique in patients with PAH and/or RV dysfunction.
Investigators
Eligibility Criteria
Inclusion Criteria
- •adult cardiac surgery patients
- •pulmonary artery hypertension and/or right heart dysfunction
- •mechanical ventilation
Exclusion Criteria
- •life threatening arrhythmia
- •severe valve regurgitation
- •left ventricular ejection fraction less than 30%
- •patients with mechanical circulatory support
Arms & Interventions
patients with pulmonary artery hypertension and/or right ventricular dysfunction
Intervention: passive leg raising
patients with pulmonary artery hypertension and/or right ventricular dysfunction
Intervention: dobutamine test
patients with pulmonary artery hypertension and/or right ventricular dysfunction
Intervention: inhaled nitric oxide
Outcomes
Primary Outcomes
cardiac output by pulmonary artery catheter
Time Frame: 30 minutes after nitric oxide inhalation
measuring cardiac output using pulmonary artery catheter
cardiac output by electrical cardiometry
Time Frame: 30 minutes after nitric oxide inhalation
measuring cardiac output using electrical cardiometry