Comparative Study of Ultrasound Guided Combined Interscalene and Supraclavicular Brachial Plexus Block Versus General Anesthesia for Brachioaxillary Surgery in Renal Failure Patient
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- graft potency
研究概览
简要总结
The aim of this study is to evaluate the efficacy of combined supraclavicular and interscalene brachial plexus block in brachio-axillary surgeries in chronic renal failure as a sole anesthetic technique in comparison to general anesthesia.
详细描述
This randomized open blinded end-point pilot study was implemented at Mansoura University Hospitals. After acceptance of Institutional Research Board (No: MS/17.08.26), sixty patients of chronic renal failure, The American Society of Anesthesiologists (ASA) III, aged from 20 to 60 years old of either sex and planned for brachioaxillary graft interposition vascular surgery were enrolled.
Patients refusal, have allergy to local anesthetic, neurological, neuromuscular, psychiatric disorders, uncompensated hepatic, respiratory or cardiac disease, uncontrolled seizures, coagulation disorders, infection at the block injection site, body mass index more than 30 were excluded.
Written informed consents were obtained. Patients were classified using closed envelop method into two groups; group (GA) received general anesthesia; group (RA) received combined supraclavicular and interscalene block, each group were carried on 30 patients.
All patients were subjected to the preoperative assessment including history taking, clinical examination and assessment of ASA score. All patients subjected to dialysis session one day before the surgery. Basal laboratory investigation as complete blood count, coagulation profile (prothrombin time, international normalized ratio and activated partial thromboplastin time), arterial blood gases, Electrocardiography and echocardiography were done after dialysis.
After an overnight fasting, patients admitted to preanesthetic room where an intravenous (IV) cannula was inserted in the contralateral upper limb. Standard monitoring was applied to the patient include heart rate (HR), noninvasive blood pressure (NIBP), peripheral oxygen saturation (SpO2).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 60 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •sixty patients of chronic renal failure,
- •aged from 20 to 60 years old
- •of either sex
- •planned for brachioaxillary graft interposition vascular surgery were enrolled.
排除标准
- •Patients refusal,
- •have allergy to local anesthetic,
- •neurological, neuromuscular, psychiatric disorders,
- •uncompensated hepatic, respiratory or cardiac disease,
- •uncontrolled seizures,
- •coagulation disorders,
- •infection at the block injection site,
- •body mass index more than 30
结局指标
主要结局
graft potency
时间窗: up to one month after surgery
by doppler
Pain assessment by numerical rating scale
时间窗: 24 hours after surgery
was explained to all candidates (zero = no pain and 10 = the worst pain)
satisfaction of the surgeon to the combined block supraclavicular and interscalene during operation
时间窗: 3 hours
by VAS from 0 to 100 as 0 represents unsatisfied and 100 represents satisfied
satisfaction of the patients to the combined block
时间窗: 3 hours
by VAS from 0 to 100 as 0 represents unsatisfied and 100 represents satisfied
次要结局
- The onset and duration of sensory and motor block(30 minutes after block)
- time to first intravenous analgesic requirement(24 hours after surgery)
- Number of times of needed analgesia(24 hours after surgery)
研究者
Nevert Adel
MD Lecturer of Anesthesia and Surgical Intensive Care
Mansoura University
