Comparative evaluation of effect of Dexamethasone via different routes on post BMP pain in patients with apical periodontitis- A randomized placebo-controlled trial
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
研究概览
简要总结
This randomized placebo-controlled clinical trial aims to evaluate and compare the effectiveness of dexamethasone administered via different routes in reducing postoperative pain following biomechanical preparation in patients with apical periodontitis. Sixty systemically healthy patients aged 20 to 40 years with preoperative pain VAS more than 5 will be randomly allocated into five groups: placebo calcium hydroxide with saline, calcium hydroxide mixed with dexamethasone, dexamethasone as an intracanal irrigant, dexamethasone as an adjunct with infiltration or block anesthesia, and dexamethasone via intraligamentary injection. Postoperative pain will be assessed using a Visual Analog Scale at 6, 12, 24, 48, and 72 hours. The study aims to determine whether the route of dexamethasone administration influences postoperative pain control following endodontic treatment in teeth with apical periodontitis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- All
入选标准
- •t with preoperative VAS score more than 5 Pt aged 20-40 years who are systemically healthy Pt diagnosed with apical periodontitis needing endodontic therapy.
排除标准
- •History of allergy to LA and any other drug used in the study Pts who are medically compromised Pts who have taken analgesics or steroids 24 hrs before reporting.
- •Retreatment cases, Calcified canals, Vertical Root fracture.
研究者
Dr Lavanya Prakash
I.T.S. DENTAL COLLEGE, GREATER NOIDA