Hormonal changes in aggressive behavior, an idiographic study - Hormonal changes in aggressive behaviour

Erasmus MC, Universitair Medisch Centrum Rotterdam0 sites6 target enrollmentStarted: TBDLast updated: April 23, 2024

Conditions

Trial Snapshot

No summary available.

•The following participants will be included to the study:
•- Participants without any psychiatric disorder. These will be participants who are confronted with aggressive behaviour in their professional daily life, but do not initiate this behaviour (e.g. mental health nurse, policeman).
•- Psychotic patients, who have florid psychotic symptoms. They have an axis-I diagnosis of schizophrenia, according to the DSM IV criteria (American Psychiatric Association, 2000) as assessed by a psychiatrist. They have no axis-II diagnosis.
•- Antisocial personality disordered patients; according to the DSM IV criteria (American Psychiatric Association, 2000) as assessed by a psychiatrist. They have no axis-I diagnosis and have a PCL-r score <26.
•- Anti-social personality disordered patients, according to the DSM IV criteria (American Psychiatric Association, 2000) as assessed by a psychiatrist. They have no axis-I diagnosis and a PCL-r score >26.;In this study, only male participants are included, as it is thought that the hormonal fluctuations in the female reproductive cycle might interact with all our hormonal parameters, especially with the oxytocin levels. Apart from that, the majority of patients treated in the Dutch *TBS* clinics is male.

•Participants who are not able to fulfil the intensive measurements because of their severe psychiatric symptoms will be excluded. To determine whether a patient is able to participate in the study, the psychiatrist who treats the patient will be consulted.

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