Influence of Erythromycin ethyl succinate oral on establishment of feeding in preterm infants

Phase 2

• Conditions: Premature infants.; Perinatal digestive system disorder, unspecified

• Registration Number: IRCT2015121925591N1
• Lead Sponsor: Iran University of Medical Sciences Research Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Infants less than 32 weeks gestational age or weighting less than 1800 g with minimum age of 5 days and clinically stable (Normal blood pressure, not having episodes of bradycardia and hypoxemia); Feeding intolerance for less than 75 milliliters per kilogram per day in 14 days; material remaining in the stomach for more than 50% in 3 hours before, which occurred at least two times during the 24 hours; Vomiting more than 30% of gastric residues in 3 hours that happened at least three times

Exclusion criteria: Lethal congenital malformations congenital or chromosomal disorders; Cyanotic heart disease; Diseases of the gastrointestinal tract obstruction (Mal rotation, Atresia and Omphalocele, etc.); Gastrointestinal surgeries in 14 days ago; NEC suspected or confirmed in the last 7 days; Definite or clinical sepsis; Metabolic disorders or electrolytic; Treatment with any of the following medications at the onset of feeding intolerance (Fentanyl , Indomethacin, Pancuronioum)

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Feeding tolerance of preterm infants. Timepoint: 5 days after birth less than 32 weeks, less than 1800 gr. Method of measurement: Weight.