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临床试验/CTRI/2025/08/093348
CTRI/2025/08/093348尚未招募不适用

Clinical profile and outcomes of young adults (18- 40 years) admitted to the ICU: A Prospective Cohort study

Sri Ramachandra Institute of Higher Education and Research1 个研究点 分布在 1 个国家目标入组 250 人开始时间: 2025年8月31日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
250
试验地点
1
主要终点
ICU mortality rate among young adults

研究概览

简要总结

Young adults, typically aged 18 to 40 years, are generally considered to be in good health. However, this age group is increasingly encountering severe illnesses and injuries that require admission to intensive care units (ICUs). In India, trauma, severe infections (including sepsis), acute poisoning, and exacerbations of chronic diseases are among the leading causes of ICU admission in this population. Although younger patients often have fewer comorbidities and better physiological reserves compared to older patients, they are not

immune to poor outcomes, including death and long-term disability.Despite the growing need to understand critical illness in young adults, most studies in the critical care literature focus predominantly on the elderly. Many ICU outcome studies aggregate adult data without stratifying by age, potentially obscuring age-specific trends and risk factors. Furthermore, data from high-income countries may not be directly applicable to the Indian context, where the disease burden, healthcare-seeking behaviour, and resource availability differ significantly. Given these gaps, there is a need for well-designed, prospective studies that focus specifically on young adults in the ICU. This study aims to prospectively evaluate the clinical characteristics, treatment interventions, and outcomes of patients aged 18–40 years admitted to the ICU over a one-year period. Findings from this study will provide valuable insights into risk stratification, treatment planning, and prognosis in this under-researched group.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 40.00 Year(s)(—)
性别
All

入选标准

  • Patients aged 18 to 40 years.
  • Admitted to ICU for greater than or equal to 24 hours during the study period.

排除标准

  • ICU re- admissions during the same hospitalization (only the first admission will be considered).
  • Patients or relatives who decline to provide informed consent (if required by IEC).

结局指标

主要结局

ICU mortality rate among young adults

时间窗: One year

次要结局

  • Length of ICU stay(Need of organ support)

研究者

申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

S Jessica Janet

Sri Ramachandra Institute of Higher Education and Research

研究点 (1)

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