Placental growth factor and haeme indicesto predict gestational diabetes mellitus
Not Applicable
Completed
- Conditions
- Health Condition 1: O244- Gestational diabetes mellitus
- Registration Number
- CTRI/2021/05/033724
- Lead Sponsor
- Dr Mounika Koduri
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 320
Inclusion Criteria
Inclusion Criteria: Singleton pregnancies at 11-14 weeks of gestation, at the time of combined
screening for aneuploidy and preeclampsia by ultrasound scan and maternal serum
biochemistry, who come to obstetrics and gynaecology OPD of Kasturba Hospital Manipal for
regular ANC checkup.
Exclusion Criteria
Exclusion Criteria:
1)Women who have been diagnosed with hypertensive disorders in pregnancy
2)Previous pregnancy complicated with Gestational diabetes mellitus (GDM)
3)Pre-existing diabetes mellitus detected by HbA1C >6
4)Pregnancies with chromosomal abnormal fetuses or structural defects at 11-14 weeks
5)Pregnancies diagnosed with severe Early onset IUGR
6)Those who are not willing to participate in the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) Diagnosis of GDM and its correlation with PlGF and blood parameter values at 11-14 weeks <br/ ><br>2) Correlation of Gestational age at delivery (in weeks), Birth weight of baby (in grams), <br/ ><br>Proportion of GDM with NICU admission 24 hours, rate of Live baby at the time of discharge <br/ ><br>to PIGF values.Timepoint: 1) Diagnosis of GDM and its correlation with PlGF and blood parameter values at 11 a 14 weeks <br/ ><br>2) Correlation of Gestational age at delivery (in weeks), Birth weight of baby (in grams), <br/ ><br>Proportion of GDM with NICU admission 24 hours, rate of Live baby at the time of discharge <br/ ><br>to PIGF values.
- Secondary Outcome Measures
Name Time Method 2) Correlation of Gestational age at delivery (in weeks), Birth weight of baby (in grams) at 36-40 weeks <br/ ><br>Proportion of GDM with NICU admission 24 hours, rate of Live baby at the time of discharge <br/ ><br>to PIGF values.Timepoint: 2) Correlation of Gestational age at delivery (in weeks), Birth weight of baby (in grams),at 36-40 weeks <br/ ><br>Proportion of GDM with NICU admission 24 hours, rate of Live baby at the time of discharge <br/ ><br>to PIGF values.