Screening Cardiovascular Patients for Aortic aNeurysms (SCAN)
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,000
- 试验地点
- 2
- 主要终点
- Prevalence of AAA
研究概览
简要总结
The aim of the cohort study SCAN (Screening Cardiovascular patients for Aortic aNeurysms) is to establish a screening programm for patients with a high risk for an AAA. Aortic aneurysms in these patients should be identified at an early stage and thereby AAA-associated mortality be decreased.
详细描述
A recently published meta-analysis showed a higher prevalence of aortic aneurysm (AAA) in men requiring treatment of coronary heart disaese compared to standard population. In women, however, the prevalence was not increased. Thus, the SCAN project addresses male patients who underwent coronary artery intervention in order to screen them for the presence of an AAA using duplex sonography.
The SCAN project involves the following elements:
- Informing the patient with cardiovascular risk factors about the clinical picture of AAA
- An ultrasound scan of the abdominal aorta in patients with an increased risk for AAA
- Acquisition of patient data followed by a correlation analysis for the parameters presence of AAA and cardiovascular diseases
The cohort study is part of the SCAN project which is also conducted in an similar way by Catharina Ziekenhuis Eindhoven ClinicalTrials.gov Identifier:NCT01643317.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •men with coronary artery intervention (PTCA/stenting)
- •at least 1 risk factor for AAA (hypertension, hyperlipidaemia, hyperuricemia, nicotine abuse,positive family history)
排除标准
- •life expectancy less than 1 year
- •inability to follow the instructions of the investigator (dementia, lack of time, insufficient understanding of the language)
- •insufficient compliance
结局指标
主要结局
Prevalence of AAA
时间窗: 1 year
Ultrasound screen for the presence of an AAA
次要结局
- Correlation of the number of treated vessels and AAA(1 year)
- Correlation of risk factors for AAA with risk factors for coronary artery disease(1 year)
- Prevalence of AAA in the cohort requiring treatment(1 year)
- Distribution of risk factors(1 year)
研究者
Univ.-Prof. Dr. med. Hans-Henning Eckstein
Univ.-Prof. Dr. med. Hans-Henning Eckstein
Technical University of Munich