Efficacy of quetiapine for delirium prevention in the hospitalized elderly medical patients
Not Applicable
Completed
- Conditions
- DeliriumQuetiapineDelirirumPreventionHospitalizedInternal medicineElderly
- Registration Number
- TCTR20190927001
- Lead Sponsor
- Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Thailand
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 122
Inclusion Criteria
Patient aged more than 65 years, acutely hospitalized in a medical ward.
Exclusion Criteria
Patient or family refusal, patient who was diagnosed delirium, patient who was critically ill, emergency surgery, terminal illness, unable to take medication, currently taking antipsychotics, active cardiac conditions, history of epilepsy, substance dependence or abuse, blood potassium level ≤ 3.0 mEq/L, corrected QTc ≥ 500 msec from EKG, unable to communicate, expected to be discharged within 24 hours, severe Parkinson’s disease and patient who was diagnosed dementia.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Delirium incident During intervention Confusion Assessment Method (CAM),Delirium duration During intervention Confusion Assessment Method (CAM)
- Secondary Outcome Measures
Name Time Method Delirium duration During intervention Confusion Assessment Method (CAM),ICU admission During hospital admission Patient is transferred to ICU,Mortality During hospital admission Patient death during hospital admission,Rehospitalization 90 days after patient discharge Patient record review and telephone,90-day mortality 90 days after patient discharge Patient record review and telephone