se of a drug named dexmedetomidine with local anaesthesia drug for middle thigh block in patients undergoing knee ligament surgeries and its effect on requirement of post operative pain relieving drug.
Phase 4
Completed
- Conditions
- Health Condition 1: null- Patients undergoing knee ligament reconstruction surgeries
- Registration Number
- CTRI/2016/03/006712
- Lead Sponsor
- Govt Medical College And Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 105
Inclusion Criteria
1. ASA physical status I and II of either sex
2. Age between 18 to 60 years
3. BMI >= 20 to <= 30 kg m-2
4. Scheduled for ACL reconstruction surgery.
Exclusion Criteria
1. Patients having history of substance abuse.
2. Patients with coagulopathy and bleeding disorders.
3. Preexisting peripheral neuropathy.
4. Preexisting local infection at the site of block.
5. Pregnant and lactating women.
6. Inability to understand functioning of PCA pump and VAS (Visual Analogue Scale).
7. Contraindication to study drugs ropivacaine, dexmedetomidine and morphine.
8. Patients having haemodynamic instability, hypotension, bradycardia, hepatic dysfunction.
9. Patients on regular chronic pain management drugs for the last three months.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study morphine sparing effect of dexmedetomidine as adjuvant to ropivacaine in ultrasound guided ACB following arthroscopic ACL reconstruction surgery.Timepoint: To study cumulative morphine consumption at 24 hours. Morphine consumption will be monitored at 0,2,4,6,8,12 and 24 hours interval.
- Secondary Outcome Measures
Name Time Method To study postoperative pain relief, haemodynamics and adverse effects after ultrasound guided ACB following arthroscopic ACL reconstruction surgery.Timepoint: Preoperatively (baseline),immediately after block 0, 5, 10, 15, 20, 30, 60 minutes and followed by 2, 4, 6, 8, 12 and 24 hours interval.