Effect of Various Sealers on Healing of Teeth With Apical Periodontitis: A Clinical Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 99
- 试验地点
- 2
- 主要终点
- Radiographic success
研究概览
简要总结
This study will compare the effect of three different sealers on healing of teeth with apical periodontitis after primary root canal treatment.
详细描述
Various sealers with different chemical composition and properties are available but it is yet not clear if one sealer is superior to other in terms of healing of apical periodontitis.
Three different groups of sealers will be used- a zinc oxide based sealer, an epoxy resin based sealer and a bioactive silicone based sealer. Mature mandibular permanent molar with the diagnosis of apical periodontitis (as confirmed clinically & by periapical radiograph) will be chosen for the study. Primary non surgical root canal treatment will be performed. The sealer will be randomly selected just before obturation of root canals. The patient will be allotted to one of the three groups.
- Group I: Zinc oxide eugenol sealer group. The material will be mixed according to manufacturer instructions and applied to canals using a lentulospiral and the obturation will be performed.
- Group II: Epoxy resin based sealer group. The material will be mixed according to the manufacturer's instructions and obturation will be done.
- Group III: Bioactive silicone based sealer: The material will be used according to the manufacturer's instruction and obturation will be performed
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •The inclusion criteria of the study will include:
- •Patient willing to participate in the study.
- •Age >18 years.
- •No history of antibiotic use within the past month or requiring antibiotic premedication
- •No history of prior analgesic use during past 24 hrs.
- •Mature permanent mandibular molar having apical periodontitis requiring primary root canal treatment.
- •There must be a radiographic evidence of periapical radiolucency (minimum size 2mmx2mm) and a diagnosis of pulpal necrosis, as confirmed by negative response to cold and electrical tests; and absence of bleeding on entering the pulp chamber
排除标准
- •Re-treatment
- •Unwillingness of patients
- •The presence of a difficult canal anatomy (root canals with an extreme curvature ≥30 deg), internal or external resorption and immature teeth.
- •Accident or complication during treatment (calcified canals ,inability to achieve apical patency in any canals) Immuno-compromised, diabetic, pregnant and hypertensive patients.
- •Teeth that are peridontally compromised
结局指标
主要结局
Radiographic success
时间窗: 12 months
Change in apical bone density will be measured by Periapical Index (PAI) score. PAI score equal to or less than 2 will be categorized as success.
Clinical success
时间窗: 12 months
Absence of pain, sinus tract, swelling and mobility.
次要结局
未报告次要终点