The CCUS Based Characteristic of Hemodynamic and Lung Pathology in Early Stage of Shock in ICU: The Epidemic and Prognostic Value

Completed

• Conditions: Shock

• Registration Number: NCT03082326
• Lead Sponsor: West China Hospital

Brief Summary

Shock is a common condition in critical care unit (ICU). It is extremely important that the patient accepts early goal-directed therapy (EGDT) treatment in the early stage of shock. However, several studies failed to demonstrate that the well used variables such as CVP and others could direct to a better treatment. In recent years, critical care ultrasound (CCUS) has been respected as a reliable noninvasive tool and widely used in ICU practice. With CCUS the investigators can accurately acquired the detailed information of the characteristic of the hemodynamics and lung pathology (the systole and diastole function, volume status, valve insufficiency, lung, edema, consolidation, and pleural effusion, etc.). To the investigators knowledge, there is no study investigating the epidemic of such ultrasonic variables and its value to predict to outcome. The aim of this study is to investigate the epidemic and the prognostic value of CCUS Based Characteristic of Hemodynamic and Lung pathology in Early Stage of Shock in patients admitted in ICU.

Detailed Description

Adult patients who admitted to the intensive care unit of West China hospital of sichuan university with shock from April 2016 to April 2017 enrolled.

Study Timeline

• Study Start: 2016-04-05
• Status Verified: 2017-03
• Study First Submitted: 2017-03-03
• Study First Submitted QC: 2017-03-11
• Study First Posted: 2017-03-17
• Primary Completion: 2017-06-06
• Study Completion: 2017-06-06
• Last Update Submitted: 2017-07-28
• Last Update Posted: 2017-08-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 181

Inclusion Criteria

1. SBP<90 mm Hg or MAP <70 mm Hg or SBP decrease >40mmHg or need vasoactive drugs;
2. Skin that is cold and clammy, capillary refill time >4.5s, urine output of <0.5ml/Kg.hr and lactate>2mmol/L;
3. SHOCK presented within 6 hr.

Exclusion Criteria

1. <18 years old;
2. Pregnancy;
3. Patient or family member refuse to be enrolled.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
all cause mortality	28 days

Secondary Outcome Measures

Name	Time	Method
ICU length of stay	through study completion, an average of 28 days
length of mechanical ventilation	through study completion, an average of 28 days
hospital length of stay	through study completion, an average of 28 days

Trial Locations

Locations (1)

West China Hospital,Sichuan University; 🇨🇳 Chengde, Sichuan, China