The Relationship Between Vitamin D, Fingernail Thickness and Bone Density
- Conditions
- Osteoporosis
- Registration Number
- NCT00006196
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Brief Summary
Vitamin D deficiency is common in the elderly and contributes to the increased incidence of falls, hip fracture and depression in this population. An unknown number of elderly have vitamin D resistance resulting in a functional vitamin D deficiency state. Because there are no simple procedures or blood tests that identify vitamin D resistance, its prevalence and contribution to disability in the elderly is unknown. Our inability to screen for this condition precludes our ability to initiate and monitor treatment.
Previous studies indicate that fingernail thickness correlates with vitamin D status and may therefore provide a simple cost effective procedure to not only identify patients with vitamin D deficiency but also, those with vitamin D resistance. This procedure may also provide a way to monitor an individual's response to treatment.
This study is designed to demonstrate the association between fingernail thickness and vitamin D status.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- Not specified
- females 25-75 years of age with no known bone disorders
- history of vertebral fractures or nonvertebral fractures without trauma
- prescription medications for prevention of osteoporosis (including vitamin D other than multivitamin and estrogen)
- history of malignancy other than basal cell or squamous cell cancer of the skin
- use of steroids or anticonvulsants in the 6 months prior to enrollment
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
4488 Forest Park, Suite 201
🇺🇸St. Louis, Missouri, United States