Evaluation of Integrated Predictive Index of Weaning From Mechanical Ventilation in Patients With Traumatic Brain Injury
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Result weaning mechanical ventilation in patients with traumatic brain injury,analyzing success and failure of weaning by 0.1 p and f / VT.
研究概览
简要总结
The purpose of this study is to evaluate physiological variables to the decision about the appropriate time to discontinuation of mechanical ventilation in patients with traumatic brain injury. It is expected that these variables are effective in predicting the outcome of weaning from mechanical ventilation.
详细描述
The aim of this study is to evaluate the effectiveness of integrated pressure index of airway occlusion x index breathing fast and shallow (p 0.1 x f/VT) in predicting success and failure of weaning from mechanical ventilation in patients with traumatic brain injury.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Traumatic Brain Injury (TBI)
- •Patients using artificial airway (intubation and / or tracheostomy)
- •Recovery from the acute phase of the disease underlying
- •Both sexes
- •Ventilation mode pressure support (PSV), pressure support (PS) required to ensure a tidal volume (VT) = 6 to 8 ml / kg
- •Age over 18 years
- •Hemoglobin > 7 g/dL
- •Duration of mechanical ventilation longer than 24 hours
- •Body temperature < 38 degrees
- •pH ≥ 7.30
- •PaO2 ≥ 60 mmHg with FiO2 ≤ 0.4 and PEEP ≤ 8 cmH2O
- •Glasgow Coma Scale ≥ 8 or tracheostomized
- •Sedative agents minimum dosages to to maintain values of 2 or 3 on the Ramsay Scale
排除标准
- •Admitted to the ICU with artificial airways held in other institutions
- •Surgery scheduled for the next 72 hours
- •Withdrawal of consent from parents at any stage of the research
结局指标
主要结局
Result weaning mechanical ventilation in patients with traumatic brain injury,analyzing success and failure of weaning by 0.1 p and f / VT.
时间窗: 8 months
次要结局
未报告次要终点
研究者
Camila Marques Dias
Physiotherapist
Federal University of Uberlandia