Connection between the amount of carbon dioxide in the arterial blood and the carbon dioxide exhaled by patients who are intubated for respiratory failure due to low oxygen.

Completed

• Conditions: Acute respiratory failure,

• Registration Number: CTRI/2023/05/053106

Brief Summary

This study is a prospective cross sectional observational study, comparing the partial pressure of arterial vs end tidal carbon dioxide in intubated patients with hypoxemic respiratory failure in 185 patients that will be conducted in critical care unit of Kasturba Hospital, Manipal. The primary outcome will be correlation between PaCO2 and PETCO2. The secondary outcome will be correlation of PaCO2 and PETCO2 across different levels of hypoxia measuured by PaO2/ FiO2 ratio.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-05-06
• Study Completion: 2024-03-31
• Last Update Posted: 2024-04-05

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 185

Inclusion Criteria

Patients with hypoxemic respiratory failure receiving invasive mechanical ventilation.

Exclusion Criteria

• Patients on non-invasive ventilation and tracheostomy.
• Patients intubated due to COPD and asthma and neuro-muscular disorder.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation between PaCO2 (mmHg) and PETCO2 (mmHg).	Once after intubation at the time of first ABG.

Secondary Outcome Measures

Name	Time	Method
Correlation of PaCO2 and PETCO2 across different levels of hypoxia measured by PaO2/FiO2 ratio	Once after intubation at the time of first ABG.

Trial Locations

Locations (1)

Kasturba Hospital, Manipal; 🇮🇳 Udupi, KARNATAKA, India

Kasturba Hospital, Manipal

🇮🇳Udupi, KARNATAKA, India

Garima Sharma

Principal investigator

8077300562

garima1.mchpmpl2022@learner.manipal.edu