The Effects of MAP and EtCO2 on Venous Sinus Pressures

Not Applicable

Completed

• Conditions: Idiopathic Intracranial Hypertension

• Registration Number: NCT03867461
• Lead Sponsor: Wake Forest University Health Sciences

Brief Summary

The purpose of this study is to further elaborate the role of both arterial blood pressure and end-tidal carbon dioxide concentration on measured venous pressures.

Detailed Description

To prospectively evaluate the effect of changes in end-tidal carbon dioxide and arterial blood pressure on venous sinus pressure measurements in patients undergoing venous sinus stenting under general anesthesia. Venous sinus pressure measurements will increase with increases in both arterial blood pressure and end-tidal carbon dioxide concentrations.

Study Timeline

• Study First Submitted: 2019-03-06
• Study First Submitted QC: 2019-03-07
• Study First Posted: 2019-03-08
• Status Verified: 2019-04
• Study Start: 2019-06-20
• Primary Completion: 2019-09-25
• Study Completion: 2019-09-25
• Last Update Submitted: 2020-05-08
• Last Update Posted: 2020-05-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 8

Inclusion Criteria

• Adults determined to be candidates for venous sinus stenting

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Venous Sinus Pressures	After intervention, up to 5 minutes

Secondary Outcome Measures

Name	Time	Method
Venous Sinus Diameter	After Intervention, up to 5 minutes

Trial Locations

Locations (1)

Wake Forest University Health Sciences; 🇺🇸 Winston-Salem, North Carolina, United States