Role of Apfel's Score in Predicting Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

Completed

• Conditions: APFEL RİSK SCORE; Post Operative Nausea and Vomiting (PONV)

• Registration Number: NCT06669325
• Lead Sponsor: National Medical College Birgunj

Brief Summary

The goal of this observational study is to assess the role of Apfel's score in predicting postoperative nausea and vomiting (PONV) after laparoscopic cholecystectomy in patients with symptomatic cholelithiasis. The main questions it aims to answer are:

1. Does Apfel's score accurately predict the occurrence of PONV after laparoscopic cholecystectomy?

2. Which components of Apfel's score are most strongly associated with PONV?

Participants will undergo laparoscopic cholecystectomy under general anesthesia. Researchers will calculate each participant's Apfel score preoperatively, and postoperative outcomes, such as nausea and vomiting, will be monitored for 24 to 48 hours. Researchers will compare PONV incidence among patients with varying Apfel scores to determine if higher scores correlate with a higher risk of PONV.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-03-12
• Primary Completion: 2023-02-06
• Study Completion: 2023-10-28
• Status Verified: 2024-10
• Study First Submitted: 2024-10-30
• Study First Submitted QC: 2024-10-30
• Last Update Submitted: 2024-10-31
• Study First Posted: 2024-11-01
• Last Update Posted: 2024-11-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Patients aged 18 to 90 years.
• Patient scheduled for elective laparoscopic cholecystectomy for symptomatic cholelithiasis.
• Patients who provided written informed consent to participate in the study.

Exclusion Criteria

• Patients receiving prophylactic antiemetic medications prior to surgery.
• Patients on opioid analgesics for reasons other than the surgical procedure.
• Pregnant women.
• Patients whose laparoscopic cholecystectomy was converted to open cholecystectomy during the operation.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of Postoperative Nausea and Vomiting (PONV)	Assessed for 24 hours post-surgery.	The number of patients who experience nausea and/or vomiting within 24 hours after laparoscopic cholecystectomy.

Secondary Outcome Measures

Name	Time	Method
Relationship Between Apfel's Score and PONV Incidence	Assessed for 24 hours post-surgery.	Evaluating the correlation between the Apfel's score (0-4) and the likelihood of PONV in patients after surgery.

Trial Locations

Locations (1)

National Medical College and Teaching Hospital, Birgunj; 🇳🇵 Birgunj, Madesh, Nepal