Role of Apfel's Score in Predicting Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Incidence of Postoperative Nausea and Vomiting (PONV)
研究概览
简要总结
The goal of this observational study is to assess the role of Apfel's score in predicting postoperative nausea and vomiting (PONV) after laparoscopic cholecystectomy in patients with symptomatic cholelithiasis. The main questions it aims to answer are:
- Does Apfel's score accurately predict the occurrence of PONV after laparoscopic cholecystectomy?
- Which components of Apfel's score are most strongly associated with PONV?
Participants will undergo laparoscopic cholecystectomy under general anesthesia. Researchers will calculate each participant's Apfel score preoperatively, and postoperative outcomes, such as nausea and vomiting, will be monitored for 24 to 48 hours. Researchers will compare PONV incidence among patients with varying Apfel scores to determine if higher scores correlate with a higher risk of PONV.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18 to 90 years.
- •Patient scheduled for elective laparoscopic cholecystectomy for symptomatic cholelithiasis.
- •Patients who provided written informed consent to participate in the study.
排除标准
- •Patients receiving prophylactic antiemetic medications prior to surgery.
- •Patients on opioid analgesics for reasons other than the surgical procedure.
- •Pregnant women.
- •Patients whose laparoscopic cholecystectomy was converted to open cholecystectomy during the operation.
结局指标
主要结局
Incidence of Postoperative Nausea and Vomiting (PONV)
时间窗: Assessed for 24 hours post-surgery.
The number of patients who experience nausea and/or vomiting within 24 hours after laparoscopic cholecystectomy.
次要结局
- Relationship Between Apfel's Score and PONV Incidence(Assessed for 24 hours post-surgery.)
研究者
Rajendra Dhakal
Clinical Professor
National Medical College Birgunj