Comparison of tracheal tubes for children's tracheas intubatio
Not Applicable
- Conditions
- hernia inguinal, hidroceleC23.300.707.374.875C12.294.882
- Registration Number
- RBR-3y357v
- Lead Sponsor
- Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, UNESP
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Data analysis completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Children undergoing general anesthesia; aged between 3 and 13 years; both genders; physical status 1 or 2 according to American Society of Anesthesiologists; minor or medium level surgery
Exclusion Criteria
Oropharyngeal and neck malformations and distortions; patients who had already been intubated or tracheostomised; previous presence of stridor or dysphonia; laryngeal or oropharyngeal illness or surgery; requirement for the introduction of a nasogastric or orogastric tube; more than two attempts at tracheal intubation; use of corticosteroids during the perioperative period; the use of local anaesthetic agents administered through a route other than that used to fill the tracheal tube cuffs
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction of the occurrence of sore throat in postoperative period evaluated by face pain scale, ranging from 0 (no pain) to 10 (maximum pain) and recorded as percentage of occurrence;Outcome evaluated:<br>Sore throat at the post anesthesia care unit (values are % of occurrence):<br>Group Air (control): 12.2%; Group Normal saline: 12.2%; Group 0.5% Alkalinized lidocaine: 2.4%; Group 1% Alkalinized lidocaine: 2.4% (qui-square test, p = 0.12).<br>Sore throat 8 hours after tracheal extubation (values are % of occurrence):<br>Group Air (control): 22.0%; Group Normal saline: 9.8%; Group 0.5% Alkalinized lidocaine: 4.8%; Group 1% Alkalinized lidocaine: 2.4% (qui-square test, p = 0.015). Then, pairwise comparison performed: Group Air vs. Group 0.5% Alkalinized lidocaine, p < 0.05; Group Air vs. Group 1% Alkalinized lidocaine, p < 0.05. All other comparisons, p > 0.05.
- Secondary Outcome Measures
Name Time Method Measurement of plasma levels of lidocaine, by blood sample collected 30 minutes after tracheal intubation;Outcome evaluated:<br>Plasma lidocaine concentration. Values are mean and standard deviation, between parentheses, and are expressed as ng/dl:<br>Group 0.5% Alkalinized lidocaine: 48.4 (53.7)<br>Group 1% Alkalinized lidocaine: 77.4 (217.61)<br>p = 0.56