Effect of exercise on older adults who have decreased muscle strength, muscle mass, and quality of life.
- Conditions
- Other specified disorders of muscle,
- Registration Number
- CTRI/2022/10/046680
- Lead Sponsor
- Prabal Kumar
- Brief Summary
With the growing population of the elderly around the world, the number of people affected by sarcopenia is expected to rise and will face the necessity to relocate to long term care settings. The sarcopenia reduces the muscle parameters, decline functional activities, and reduced quality of the life making them vulnerable to frailty. Sarcopenic changes are associated with number of adverse events like falls, fracture, loss of independence, and frequent hospitalization which increases health care cost bear by older adults residing in long term care setting. Hence, there is a need to preserve and improve the muscle parameters, functional activities, and quality of life of older adults with sarcopenia residing in long term care settings. Thus the objective of the study are:
Phase 1: To design and validate Reablement Strategies targeting Sarcopenia (ReStart-S) among older adults residing in long term care settings
Phase 2: To evaluate the effect of the ReStart-S program on muscle strength, physical performance, muscle mass, biomarkers, activities of daily living and quality of life among older adults residing in long term care settings
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 78
(1) either gender, (2) more than or equal to 60 years of age to less than or equal to 99 years, (3) Barthel index more than or equal to 60 points, (4) Mini cog score more than or equal to 2 and normal clock drawing, (5) Sarcopenia as per the Asian Working Group for Sarcopenia 2019 (AWGS 2019) guidelines cut-off that is: (a) Appendicular skeletal muscle mass: <7.0 kilogram per meter square in men and <5.7 kilogram per meter square in women, (b) Hand Grip Strength: <28.0 kilogram for men and <18.0 kilogram for women, (c) Short Physical Performance Battery: less than or equal to 9.
(1) Critically ill/ Terminally ill/ Active infection, (2) Pacemaker and any metal implant, (3) Bed bound/wheelchair bound, (4) Acute onset (less than 30 days) of cardiorespiratory/neurological/renal/orthopaedic disease.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hand Grip Strength (HGS, Kilogram) 0 week (baseline assessment), 6 weeks (minimum intervention duration), 12 weeks (minimum follow up duration post intervention)
- Secondary Outcome Measures
Name Time Method (1) Physical performance: Short Physical Performance Battery (SPPB), (2) Muscle mass: Appendicular skeletal muscle mass (ASM, Kilogram/meter square), (3) Biomarker: C-terminal Agrin Fragment (CAF, nanograms per milliliter), (4) Activities of daily living: Katz Index of Independence in Activities of Daily Living, (5) Quality of life- Sarcopenia and Quality of Life questionnaire (SarQoL) 0 week (baseline assessment), 6 weeks (minimum intervention duration), 12 weeks (minimum follow up duration post intervention)
Trial Locations
- Locations (6)
A V BALIGA HOME FOR SENIOR CITIZENS
🇮🇳Udupi, KARNATAKA, India
KARUNALAYA CHARITABLE TRUST
🇮🇳Udupi, KARNATAKA, India
KUTEERA OLD AGE HOME
🇮🇳Udupi, KARNATAKA, India
OZANAM HOME FOR THE AGED
🇮🇳Udupi, KARNATAKA, India
SRI KRISHNA OLD AGE HOME
🇮🇳Udupi, KARNATAKA, India
VISHRANTHI DHAMA OLD AGE HOME
🇮🇳Udupi, KARNATAKA, India
A V BALIGA HOME FOR SENIOR CITIZENS🇮🇳Udupi, KARNATAKA, IndiaPrabal KumarPrincipal investigator9870656646kprabal000@gmail.com