Taiwan Health Promotion Intervention Study for Elders
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,080
- 主要终点
- Change from baseline frailty score at 12 months
研究概览
简要总结
Objectives: 1-year multidomain health promotion on prevention of physical and cognitive decline for community-living older people.
Design:
Methods: Randomized controlled trial
Setting:
Five cities(Taipei, Taichung, Kaohsiung, Kinmen, I-Lan) in Taiwan Participants: age 65 or older community-dwelling prefrail or frail adults Intervention: 1-year multidomain health promotion (physical, cognitive, nutritional intervention)
Measurements:
Primary outcome includes frailty status and cognitive performance. Secondary outcomes include depressive symptoms, nutrition assessment, and functional capacity; All the variables were measured at 0, 6, 12 months. The effect of intervention was investigated by intention-to-treat analysis.
详细描述
Eligibility criteria includes: community-dwelling older people aged 65 or older, and those with confirmed diagnosis of dementia or dependent on activities of daily living were excluded.
Primary outcome includes frailty status measured by CHS frailty score. general and sub-domain cognitive performance measured by Montreal Cognitive Assessment (MoCA). Secondary outcomes include depressive symptoms, nutrition assessment, and functional capacity; which were evaluated by 5-item Geriatric Depression scale(GDS-5), Mini-nutrition Assessment(MNA), and instrumental activities of daily living (IADL) individually.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Prefrail or frail community-dwelling people
排除标准
- •Institutionalized or ADL dependent
- •Diagnosed dementia
- •Limited life expectancy
结局指标
主要结局
Change from baseline frailty score at 12 months
时间窗: 12 months
Measured by Cardiovascular Health Study(CHS) definition
次要结局
未报告次要终点
研究者
vghtpe user
Principal investigator
Taipei Veterans General Hospital, Taiwan