Investigating the effect of the combination of Fentanyl-Magnesium sulfate and Fentanyl-Midazolam on hemodynamic status and sedation rate
Phase 3
Recruiting
- Conditions
- Mechanical ventilation in the ICU.
- Registration Number
- IRCT20160307026950N44
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Age 18 to 75 years
Bedridden in ICU
Requires mechanical ventilation for at least 12 hours
Consent to participate in the study
Exclusion Criteria
Central nervous system disorders
Weight more than 120 kg
Use of neuromuscular blockers
General or regional anesthesia
allergy to the drugs used
Tracheostomy patients
pregnant and breastfeeding women
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The amount of sedation. Timepoint: Every hour to 24 hours. Method of measurement: Richmond Anxiety-Sedation Scale.;Pain amount. Timepoint: Every hour to 24 hours. Method of measurement: Visual Analogue Scale.;Blood Pressure. Timepoint: Every hour to 24 hours. Method of measurement: Sphygmomanometer.;Heart Rate. Timepoint: Every hour to 24 hours. Method of measurement: Electrocardiogram.
- Secondary Outcome Measures
Name Time Method