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Clinical Trials/NCT06015932
NCT06015932
Recruiting
Not Applicable

A Non-Randomized Translational Trial of Cognitive Behavioral Cancer Stress Management (CBCSM) and Its Effects on Cancer Distress

Mayo Clinic1 site in 1 country400 target enrollmentDecember 20, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hematopoietic and Lymphoid System Neoplasm
Sponsor
Mayo Clinic
Enrollment
400
Locations
1
Primary Endpoint
Change in post-traumatic stress (PTS) score
Status
Recruiting
Last Updated
9 months ago

Overview

Brief Summary

This clinical trial tests how well cognitive behavioral cancer stress management (CBCSM) group sessions work to decrease psychological distress in cancer patients. CBCSM teaches patients how to recognize and reduce the impacts of cancer associated stress on the biological, psychological, and social life domains.

Detailed Description

PRIMARY OBJECTIVE: I. To reduce psychological stress. SECONDARY OBJECTIVES: I. To increase post-traumatic growth (PTG). II. To increase patient self-efficacy in utilizing therapy skills. III. To estimate patient acceptability and feasibility of conducting CBCSM within the clinical setting. IV. To estimate differences of conducting CBCSM virtually during the Public Health Emergency (PHE) versus in person pre-PHE. V. To estimate differences of conducting CBCSM post PHE virtually with limitation to Minnesota patients only. VI. To explore the difference using the same therapy in patients with advanced, metastatic disease in a individual setting versus patients without the advanced, metastatic disease in a group setting. OUTLINE: Patients are assigned to 1 of 2 groups. GROUP I: Patients participate in five CBCSM group sessions on study. Patients complete questionnaires throughout the trial and during follow-up at 1, 3, 6, and 12 months. GROUP II: Patients complete questionnaires throughout the trial and during follow-up at 1, 3, 6, and 12 months.

Registry
clinicaltrials.gov
Start Date
December 20, 2017
End Date
December 1, 2029
Last Updated
9 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Shawna L. Ehlers, Ph.D., L.P.

Principal Investigator

Mayo Clinic

Eligibility Criteria

Inclusion Criteria

  • Eligible for the cognitive behavioral cancer stress management (CBCSM) clinical service
  • Cancer diagnosis with predicted survival \> 1 year
  • Cancer treatment within past 1 year or treatment planning in progress
  • Age \>= 18-years
  • Moderate distress screen, indicated by Impact of Event Scale-Revised (IES-R) score \>= 14 or clinical judgment
  • Written informed research consent

Exclusion Criteria

  • Inability to actively participate in and learn from group therapy (e.g., psychotic symptoms, neurological condition, personality pathology) as determined by clinical judgment in clinical consultation (Individual therapy or alternative group therapy will be offered)

Outcomes

Primary Outcomes

Change in post-traumatic stress (PTS) score

Time Frame: At baseline, 1, 3, 6, and 12 months

Each item on the PTS is rated on a 5-point scale (0=Not at all; 1=A little bit; 2=Moderately; 3=Quite a bit, and 4=Extremely). The total score can range from 0 to 36 with higher scores indicating greater severity of posttraumatic stress disorder.

Secondary Outcomes

  • Change in post-traumatic growth (PTG) score(At baseline, 1, 3, 6, and 12 months)
  • Change in self-efficacy score(At baseline, 1, 3, 6, and 12 months)
  • Patient acceptability and satisfaction(Baseline to 12 months)
  • Patient attendance and feasibility(Baseline to 12 months)
  • Anxiety(At baseline, 1, 3, 6, and 12 months)
  • Depression(At baseline, 1, 3, 6, and 12 months)

Study Sites (1)

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