Comparison of Efficacy of Ultrasound guided Suprascapular Nerve Block Versus Intra-Articular Platelet Rich Plasma in Periarthritis Shoulder Pain: A Randomized Controlled Trial
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Visual Analogue Scale
研究概览
简要总结
American academy of orthopaedic surgeons defines periarthritis shoulder (PA shoulder) as a condition of uncertain aetiology characterized by significant restriction of both active and passive range of motion that occurs in the absence of a known intrinsic shoulder disorder.[1]
This condition also commonly known as “Adhesive capsulitis†and “frozen shoulder†has a prevalence of 2-5% in general population. It is 2 to 4 times more common in women than man and affects middle age and elderly people.[2]
It is characterized by painful, restricted shoulder range of motion (ROM) in patients with normal radiographs. Treatment for periarthritis shoulder includes non-steroidal anti- inflammatory drugs, electrotherapy, exercise regimens, intra-articular steroid injections, suprascapular nerve blocks, manipulation under anesthesia, hydrodilatation, arthroscopic capsular release and recent modalities like platelet rich plasma.[2]
Suprascapular nerve block is known to be a safe and effective treatment for chronic shoulder pain in conditions like periarthritis shoulder irreparable rotator cuff tear, calcific tendinitis, stroke sequalae.[3]
Platelet rich plasma (PRP) is component of plasma containing higher concentration of platelets and growth factors. It is obtained after centrifugation of patient’s own blood. Being rich in growth factors it is believed to increase vascularity and improve healing process. Considering these properties, intra-articular PRP injections might prove beneficial for PA shoulder patient. Therefore, its efficacy needs to be examined and compared with other
available treatments.[4]
Despite availability of above treatment option for years, evidence regarding their efficacy is unclear. With origin of newer treatment options like platelet rich plasma, it has become important to study effect of conventional methods and their comparison with recent advance methods.
Through this study, we are comparing efficacy of intra-articular platelet rich plasma injection with suprascapular nerve block in patients with periarthritis shoulder.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Age more than 18 years, clinically diagnosed with periarthritis shoulder Duration of symptoms more than 4 weeks Normal anteroposterior radiographs of the glenohumeral joint.
排除标准
- •History of shoulder trauma, dislocation or fractures in the shoulder area, History of injection in the involved shoulder during the preceding 6 months, Bleeding disorders, Uncontrolled diabetes mellitus, Active infection at site of injection, History of allergy to local anaesthetics, Use of anticoagulant drugs in past 7 days and Affected shoulder surgery in past 1 year.
- •Patients who are pregnant or breastfeeding.
结局指标
主要结局
Visual Analogue Scale
时间窗: At the time of intervention, then at 2 weeks , 6 weeks and 12 weeks post intervention.
次要结局
- Shoulder Pain and Disability Index(Range Of Motion)
研究者
Dr Vinay Kanaujia
Uttar Pradesh University Of Medical Sciences