Comparing the effectiveness of Ketamine-Dexmedetomidine vs. ketamine-midazolam combination for providing sedation and analgesia in children undergoing infraumbilical surgeries under caudal anesthesia.
Phase 4
- Conditions
- Health Condition 1: Q531- Undescended testicle, unilateralHealth Condition 2: K409- Unilateral inguinal hernia, without obstruction or gangreneHealth Condition 3: K37- Unspecified appendicitis
- Registration Number
- CTRI/2024/03/063544
- Lead Sponsor
- Sardar Patel Medical College Bikaner Rahasthan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. ASA Grade I to III
2. Infraumbilical elective surgeries
Exclusion Criteria
1.Patient’s parents or caretaker’s refusal.
2.Allergy to the drugs used in the study.
3.Pre-existing neuromuscular disorder or spinal deformities.
4.Raised ICT (Intra Cranial Tension).
5.Coagulation defect.
6.Local site infection.
7.Severe hypovolemia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To Compare the Perioperative Sedo-Analgesic Efficacy of Intravenous Ketamine-Dexmedetomidine and Ketamine-Midazolam Combination in Paediatric Patients Posted for Infraumbilical Surgeries Under Caudal Epidural Block to- <br/ ><br> 1. observe limb movement at time of needle prick for caudal block. <br/ ><br> 2. observe onset time and level of sedation. <br/ ><br> 3. observe intraoperative hemodynamic parameters. <br/ ><br> <br/ ><br>Timepoint: till end of the surgery. <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1)To observe quality and duration of postoperative sedation. <br/ ><br>2)Surgeon satisfaction. <br/ ><br>3)To observe any complications and side effects. <br/ ><br>Timepoint: till the drug effect is over.